[15] SMU 48-21 South Florida [108] 2019-05-16 20:00
Stadium: Raymond James Stadium Round: 1
Home Manager: Sonny Dykes Away Manager: Charlie Strong
Head to Head
| NCAAF | 2016/11/20 00:00 | South Florida v SMU | L | 35-27 |
| NCAAF | 2015/10/24 20:00 | South Florida v SMU | L | 38-14 |
| NCAAF | 2014/11/16 01:00 | SMU v South Florida | L | 13-14 |
Home History
| NCAAF | 2018/11/24 20:30 | SMU v Tulsa | L | 24-27 |
| NCAAF | 2018/11/17 02:00 | Memphis v SMU | L | 28-18 |
| NCAAF | 2018/11/10 17:00 | SMU v Connecticut | W | 62-50 |
| NCAAF | 2018/11/03 23:00 | Houston v SMU | W | 31-45 |
| NCAAF | 2018/10/27 19:30 | Cincinnati v SMU | L | 26-20 |
| NCAAF | 2018/10/20 19:30 | SMU v Tulane | W | 27-23 |
| NCAAF | 2018/10/06 23:00 | SMU v Central Florida | L | 20-48 |
| NCAAF | 2018/09/29 23:00 | Houston Christian v SMU | W | 27-63 |
Away History
| NCAAF | 2018/12/21 01:00 | Marshall v South Florida | L | 38-20 |
| NCAAF | 2018/11/23 21:00 | Central Florida v South Florida | L | 38-10 |
| NCAAF | 2018/11/17 17:00 | South Florida v Temple | L | 17-27 |
| NCAAF | 2018/11/11 00:00 | South Florida v Cincinnati | L | 23-35 |
| NCAAF | 2018/11/03 19:30 | Tulane v South Florida | L | 41-15 |
| NCAAF | 2018/10/27 19:30 | South Florida v Houston | L | 36-57 |
| NCAAF | 2018/10/20 23:00 | Connecticut v South Florida | W | 30-38 |
| NCAAF | 2018/10/12 23:00 | South Florida v Tulsa | W | 25-24 |