[15] FLA Panthers 2-3 BUF Sabres [21] 2019-08-07 08:00
Stadium: KeyBank Center
Home Manager: Ralph Krueger Away Manager: Joel Quenneville
Head to Head
| NHL | 2019/02/20 00:00 | BUF Sabres v FLA Panthers | W | 2-4 |
| NHL | 2019/01/04 00:00 | FLA Panthers v BUF Sabres | L | 3-4 |
| NHL | 2018/12/19 00:00 | FLA Panthers v BUF Sabres | W | 5-2 |
| NHL | 2018/12/01 00:00 | BUF Sabres v FLA Panthers | W | 2-3 |
| NHL | 2018/04/07 23:00 | BUF Sabres v FLA Panthers | W | 3-4 |
| NHL | 2018/03/03 00:30 | BUF Sabres v FLA Panthers | W | 1-4 |
| NHL | 2018/02/02 00:00 | FLA Panthers v BUF Sabres | W | 4-2 |
| NHL | 2017/11/11 00:00 | FLA Panthers v BUF Sabres | W | 4-1 |
Home History
| NHL | 2019/04/06 23:00 | NJ Devils v FLA Panthers | L | 4-3 |
| NHL | 2019/04/04 23:00 | NY Islanders v FLA Panthers | L | 2-1 |
| NHL | 2019/04/01 23:00 | WAS Capitals v FLA Panthers | W | 3-5 |
| NHL | 2019/03/30 17:00 | FLA Panthers v BOS Bruins | W | 4-1 |
| NHL | 2019/03/28 23:30 | FLA Panthers v OTT Senators | W | 5-2 |
| NHL | 2019/03/26 23:30 | FLA Panthers v MTL Canadiens | L | 1-6 |
| NHL | 2019/03/25 23:00 | FLA Panthers v TOR Maple Leafs | L | 5-7 |
| NHL | 2019/03/23 23:00 | BOS Bruins v FLA Panthers | L | 7-3 |
Away History
| NHL | 2019/04/06 23:00 | BUF Sabres v DET Red Wings | W | 7-1 |
| NHL | 2019/04/04 23:00 | OTT Senators v BUF Sabres | W | 2-5 |
| NHL | 2019/04/02 23:00 | NSH Predators v BUF Sabres | L | 3-2 |
| NHL | 2019/03/31 22:00 | CLB Blue Jackets v BUF Sabres | L | 4-0 |
| NHL | 2019/03/30 23:00 | BUF Sabres v NY Islanders | L | 1-5 |
| NHL | 2019/03/28 23:00 | DET Red Wings v BUF Sabres | L | 5-4 |
| NHL | 2019/03/26 23:30 | BUF Sabres v OTT Senators | L | 0-4 |
| NHL | 2019/03/25 23:00 | BUF Sabres v NJ Devils | L | 1-3 |