[46] Danielle Collins 2-6,6-4,6-10 Serena Williams [11] 2020-10-06 10:20
Stadium: Margaret Court Arena Round: 27 Ground: Hardcourt outdoor
Home History
| French Open Women | 2020/10/06 09:00 | Ons Jabeur v Danielle Rose Collins | 4-6,6-4,4-6 |
| French Open Women | 2020/10/03 16:55 | Danielle Rose Collins v Garbine Muguruza | 7-5,2-6,6-4 |
| French Open Women | 2020/10/01 09:00 | Clara Tauson v Danielle Rose Collins | 2-6,3-6 |
| French Open Women | 2020/09/29 09:00 | Monica Niculescu v Danielle Rose Collins | 6-2,2-6,1-6 |
| US Open Women | 2020/08/31 20:10 | Danielle Rose Collins v Anett Kontaveit | 7-5,2-6,2-6 |
| WTA New York | 2020/08/23 20:55 | Danielle Rose Collins v Jil Teichmann | 3-6,3-6 |
| US Invitational Women | 2020/06/27 00:05 | Danielle Rose Collins v Victoria Azarenka | 6-1,7-5 |
| US Invitational Women | 2020/06/23 23:40 | Danielle Rose Collins v Amanda Anisimova | 5-7,4-6 |
Away History
| French Open Women | 2020/09/28 13:05 | Kristie Ahn v Serena Williams | 6-7,0-6 |
| US Open Women | 2020/09/11 01:30 | Serena Williams v Victoria Azarenka | 6-1,3-6,3-6 |
| US Open Women | 2020/09/09 16:00 | Tsvetana Pironkova v Serena Williams | 6-4,3-6,2-6 |
| US Open Women | 2020/09/07 16:00 | Maria Sakkari v Serena Williams | 3-6,7-6,3-6 |
| US Open Women | 2020/09/05 18:10 | Sloane Stephens v Serena Williams | 6-2,2-6,2-6 |
| US Open Women | 2020/09/03 23:00 | Margarita Betova v Serena Williams | 2-6,4-6 |
| US Open Women | 2020/09/01 21:05 | Kristie Ahn v Serena Williams | 5-7,3-6 |
| WTA New York | 2020/08/26 00:40 | Maria Sakkari v Serena Williams | 5-7,7-6,6-1 |