[10] LA Chargers 29-41 HOU Texans [30] 2021-12-10 12:00
Stadium: NRG Stadium Round: 1
Home Manager: Brandon Staley Away Manager: David Culley
Head to Head
| NFL | 2019/09/22 20:25 | HOU Texans v LA Chargers | L | 27-20 |
| NFL | 2016/11/27 18:00 | LA Chargers v HOU Texans | W | 21-13 |
Home History
| NFL | 2021/12/05 18:00 | LA Chargers v CIN Bengals | W | 41-22 |
| NFL | 2021/11/28 21:05 | LA Chargers v DEN Broncos | L | 13-28 |
| NFL | 2021/11/22 01:20 | PIT Steelers v LA Chargers | W | 37-41 |
| NFL | 2021/11/14 21:05 | MIN Vikings v LA Chargers | L | 27-20 |
| NFL | 2021/11/07 21:05 | LA Chargers v PHI Eagles | W | 27-24 |
| NFL | 2021/10/31 20:05 | NE Patriots v LA Chargers | L | 27-24 |
| NFL | 2021/10/17 17:00 | LA Chargers v BAL Ravens | L | 6-34 |
| NFL | 2021/10/10 20:05 | CLE Browns v LA Chargers | W | 42-47 |
Away History
| NFL | 2021/12/05 18:00 | IND Colts v HOU Texans | L | 31-0 |
| NFL | 2021/11/28 18:00 | NY Jets v HOU Texans | L | 21-14 |
| NFL | 2021/11/21 18:00 | HOU Texans v TEN Titans | W | 22-13 |
| NFL | 2021/11/07 18:00 | HOU Texans v MIA Dolphins | L | 9-17 |
| NFL | 2021/10/31 17:00 | LA Rams v HOU Texans | L | 38-22 |
| NFL | 2021/10/24 20:25 | HOU Texans v ARZ Cardinals | L | 5-31 |
| NFL | 2021/10/17 17:00 | HOU Texans v IND Colts | L | 3-31 |
| NFL | 2021/10/10 17:00 | NE Patriots v HOU Texans | L | 25-22 |