Head to Head
| MLB Exhibition | 2021/03/20 20:05 | CLE Guardians v CHI White Sox | W | 2-6 |
| MLB Spring Training | 2021/03/06 20:05 | CHI White Sox v CLE Guardians | W | 7-0 |
| MLB | 2020/09/24 22:10 | CHI White Sox v CLE Guardians | L | 4-5 |
| MLB | 2020/09/23 22:10 | CHI White Sox v CLE Guardians | L | 2-3 |
| MLB | 2020/09/22 22:10 | CHI White Sox v CLE Guardians | L | 3-5 |
| MLB | 2020/09/21 22:10 | CHI White Sox v CLE Guardians | L | 4-7 |
| MLB | 2020/08/09 23:08 | CLE Guardians v CHI White Sox | L | 5-4 |
| MLB | 2020/08/08 18:10 | CLE Guardians v CHI White Sox | L | 7-1 |
Home History
| MLB | 2021/04/03 01:38 | CHI White Sox v LA Angels | W | 12-8 |
| MLB | 2021/04/02 02:05 | CHI White Sox v LA Angels | L | 3-4 |
| MLB Exhibition | 2021/03/30 19:10 | CHI White Sox v COL Rockies | L | 1-2 |
| MLB Exhibition | 2021/03/28 20:05 | ARI Diamondbacks v CHI White Sox | W | 4-7 |
| MLB Exhibition | 2021/03/27 20:10 | CHI White Sox v COL Rockies | W | 8-2 |
| MLB Exhibition | 2021/03/26 20:10 | CHI White Sox v MIL Brewers | W | 7-5 |
| MLB Spring Training | 2021/03/25 20:05 | CIN Reds v CHI White Sox | W | 4-9 |
| MLB Exhibition | 2021/03/24 20:05 | OAK Athletics v CHI White Sox | L | 14-4 |
Away History
| MLB | 2021/04/03 17:10 | CLE Guardians v DET Tigers | L | 2-5 |
| MLB | 2021/04/01 17:10 | CLE Guardians v DET Tigers | L | 2-3 |
| MLB Exhibition | 2021/03/30 19:40 | CLE Guardians v ARI Diamondbacks | L | 2-3 |
| MLB Spring Training | 2021/03/29 19:05 | CLE Guardians v KC Royals | L | 4-5 |
| MLB Spring Training | 2021/03/28 20:05 | SD Padres v CLE Guardians | D | 3-3 |
| MLB Exhibition | 2021/03/27 19:05 | CLE Guardians v LA Dodgers | W | 9-2 |
| MLB Spring Training | 2021/03/26 20:05 | COL Rockies v CLE Guardians | W | 4-5 |
| MLB Exhibition | 2021/03/25 01:10 | CLE Guardians v ARI Diamondbacks | L | 5-6 |