[9] Spartak Moscow 1-2 FC Nizhny Novgorod [5] 2021-05-30 23:00
Stadium: Otkritie Arena Round: 3
Referee: Aleksei Vasilevich Sukhoi Home Manager: Rui Vitoria Away Manager: Aleksandr Kerzhakov
Home History
| Russia Premier League | 2021/05/16 11:00 | FC Akhmat Grozny v Spartak Moscow | D | 2-2 |
| Russia Premier League | 2021/05/10 16:00 | Spartak Moscow v FK Khimki | W | 2-1 |
| Russia Premier League | 2021/05/03 13:30 | Arsenal Tula v Spartak Moscow | W | 1-2 |
| Russia Premier League | 2021/04/25 13:30 | Spartak Moscow v CSKA Moscow | W | 1-0 |
| Russia Premier League | 2021/04/18 16:00 | Spartak Moscow v FC Ufa | L | 0-3 |
| Russia Premier League | 2021/04/11 16:00 | Lokomotiv Moscow v Spartak Moscow | L | 2-0 |
| Russia Premier League | 2021/04/04 16:00 | Rostov v Spartak Moscow | W | 2-3 |
| Russia Premier League | 2021/03/18 16:00 | Spartak Moscow v Ural | W | 5-1 |
Away History
| Russia Division 1 | 2021/05/15 13:00 | Tom Tomsk v FC Nizhny Novgorod | D | 1-1 |
| Russia Division 1 | 2021/05/08 12:00 | Chertanovo v FC Nizhny Novgorod | W | 1-3 |
| Russia Division 1 | 2021/05/02 13:00 | FC Nizhny Novgorod v Spartak Moscow II | W | 4-0 |
| Russia Division 1 | 2021/04/28 16:00 | FC Nizhny Novgorod v FK Yenisey | L | 1-2 |
| Russia Division 1 | 2021/04/24 10:00 | FC Orenburg v FC Nizhny Novgorod | L | 2-1 |
| Russia Division 1 | 2021/04/17 13:00 | FC Nizhny Novgorod v Chaika Petropavlovskaya | W | 2-0 |
| Russia Division 1 | 2021/04/11 05:00 | SKA Energia Khabarovsk v FC Nizhny Novgorod | W | 0-1 |
| Russia Division 1 | 2021/04/07 16:00 | FC Nizhny Novgorod v Veles | W | 1-0 |