[16] Santos U20 1-3 Sao Paulo U20 [1] 2021-05-11 00:00
Stadium: Centro de Treinamento Rei Pele Round: 8
Head to Head
| Brazil Serie A U20 | 2020/11/22 19:00 | Santos U20 v Sao Paulo U20 | L | 1-5 |
| Brazil Serie A U20 | 2019/08/14 19:30 | Sao Paulo U20 v Santos U20 | L | 3-1 |
| Brazil Campeonato Paulista U20 | 2017/08/09 18:00 | Santos U20 v Sao Paulo U20 | D | 2-2 |
| Brazil Campeonato Paulista U20 | 2017/05/13 18:00 | Sao Paulo U20 v Santos U20 | L | 3-1 |
| Brazil Campeonato Paulista U20 | 2016/11/20 20:00 | Sao Paulo U20 v Santos U20 | L | 2-1 |
| Brazil Campeonato Paulista U20 | 2016/11/12 18:00 | Santos U20 v Sao Paulo U20 | D | 0-0 |
Home History
| Brazil Serie A U20 | 2020/12/20 18:30 | Santos U20 v Goias U20 | W | 6-2 |
| Brazil Campeonato Paulista U20 | 2020/12/18 18:00 | Corinthians U20 v Santos U20 | L | 3-1 |
| Brazil Serie A U20 | 2020/12/13 18:30 | Internacional U20 v Santos U20 | D | 1-1 |
| Brazil Campeonato Paulista U20 | 2020/12/11 18:00 | Ferroviaria SP U20 v Santos U20 | W | 1-2 |
| Brazil Serie A U20 | 2020/12/06 19:00 | Santos U20 v Palmeiras U20 | W | 2-0 |
| Brazil Campeonato Paulista U20 | 2020/12/04 18:00 | XV Piracicaba U20 v Santos U20 | W | 5-6 |
| Brazil Serie A U20 | 2020/12/02 18:00 | Atletico Paranaense U20 v Santos U20 | L | 3-1 |
| Brazil Campeonato Paulista U20 | 2020/11/30 18:00 | Santos U20 v Portuguesa Santista U20 | D | 1-1 |
Away History
| Brazil Serie A U20 | 2021/01/03 19:00 | Atletico Paranaense U20 v Sao Paulo U20 | L | 1-0 |
| Brazil Serie A U20 | 2020/12/27 19:00 | Sao Paulo U20 v Atletico Paranaense U20 | D | 1-1 |
| Brazil Serie A U20 | 2020/12/20 19:00 | Vasco da Gama U20 v Sao Paulo U20 | L | 2-1 |
| Brazil Serie A U20 | 2020/12/13 23:00 | Sao Paulo U20 v Atletico Mineiro U20 | W | 2-0 |
| Brazil Serie A U20 | 2020/12/06 18:00 | Ceara U20 v Sao Paulo U20 | W | 1-2 |
| Brazil Campeonato Paulista U20 | 2020/12/04 18:00 | Comercial U20 v Sao Paulo U20 | L | 5-4 |
| Brazil Serie A U20 | 2020/12/03 22:00 | Sao Paulo U20 v Corinthians U20 | W | 1-0 |
| Brazil Campeonato Paulista U20 | 2020/11/30 18:00 | Sao Paulo U20 v Oeste U20 | D | 1-1 |