[3] St Pauli 3-1 Karlsruher SC [9] 2022-01-01 04:30
Stadium: Millerntor-Stadion Round: 25
Referee: Tobias Reichel Home Manager: Timo Schultz Away Manager: Christian Eichner
Head to Head
| Germany Bundesliga II | 2021/09/25 11:30 | Karlsruher SC v St Pauli | W | 1-3 |
| Germany Bundesliga II | 2021/03/06 12:00 | Karlsruher SC v St Pauli | D | 0-0 |
| Germany Bundesliga II | 2020/11/08 12:30 | St Pauli v Karlsruher SC | L | 0-3 |
| Germany Bundesliga II | 2020/05/30 11:00 | Karlsruher SC v St Pauli | D | 1-1 |
| Germany Bundesliga II | 2019/11/02 12:00 | St Pauli v Karlsruher SC | D | 2-2 |
| Europe Friendlies | 2018/07/17 16:00 | Karlsruher SC v St Pauli | L | 4-1 |
| Germany Bundesliga II | 2017/02/27 19:15 | St Pauli v Karlsruher SC | W | 5-0 |
| Germany Bundesliga II | 2016/09/18 11:30 | Karlsruher SC v St Pauli | D | 1-1 |
Home History
| Germany Bundesliga II | 2021/12/17 17:30 | Holstein Kiel v St Pauli | L | 3-0 |
| Germany Bundesliga II | 2021/12/11 19:30 | Fortuna Dusseldorf v St Pauli | D | 1-1 |
| Germany Bundesliga II | 2021/12/04 19:30 | St Pauli v Schalke | W | 2-1 |
| Germany Bundesliga II | 2021/11/28 12:30 | Nurnberg v St Pauli | W | 2-3 |
| Germany Bundesliga II | 2021/11/24 17:30 | St Pauli v Sandhausen | W | 3-1 |
| Germany Bundesliga II | 2021/11/20 12:30 | Darmstadt v St Pauli | L | 4-0 |
| Germany Bundesliga II | 2021/10/30 11:30 | Werder Bremen v St Pauli | D | 1-1 |
| Germany DFB Pokal | 2021/10/27 16:30 | Dynamo Dresden v St Pauli | W | 2-3 |
Away History
| Germany Bundesliga II | 2021/12/19 12:30 | Karlsruher SC v Hansa Rostock | D | 2-2 |
| Germany Bundesliga II | 2021/12/12 12:30 | Karlsruher SC v Heidenheim | W | 3-2 |
| Germany Bundesliga II | 2021/12/05 12:30 | Dynamo Dresden v Karlsruher SC | L | 3-1 |
| Germany Bundesliga II | 2021/11/27 12:30 | Karlsruher SC v Hannover 96 | W | 4-0 |
| Germany Bundesliga II | 2021/11/21 12:30 | FC Ingolstadt v Karlsruher SC | D | 1-1 |
| Europe Friendlies | 2021/11/11 12:00 | Karlsruher SC v SC Freiburg | L | 1-2 |
| Germany Bundesliga II | 2021/11/06 19:30 | Karlsruher SC v Hamburg | D | 1-1 |
| Germany Bundesliga II | 2021/10/31 12:30 | Karlsruher SC v Paderborn | L | 2-4 |