[4] Sevilla 1-0 Villarreal [12] 2021-09-14 07:00
Stadium: Ramon Sanchez Pizjuan Round: 16
Referee: Carlos Del Cerro Grande Home Manager: Julen Lopetegui Away Manager: Unai Emery
Head to Head
| Spain La Liga | 2021/05/16 16:30 | Villarreal v Sevilla | L | 4-0 |
| Spain La Liga | 2020/12/29 16:00 | Sevilla v Villarreal | W | 2-0 |
| Spain La Liga | 2020/06/22 17:30 | Villarreal v Sevilla | D | 2-2 |
| Spain La Liga | 2019/12/15 17:30 | Sevilla v Villarreal | L | 1-2 |
| Spain La Liga | 2019/02/17 17:30 | Villarreal v Sevilla | L | 3-0 |
| Spain La Liga | 2018/08/26 20:15 | Sevilla v Villarreal | D | 0-0 |
| Spain La Liga | 2018/04/14 11:00 | Sevilla v Villarreal | D | 2-2 |
| Spain La Liga | 2017/11/26 17:30 | Villarreal v Sevilla | W | 2-3 |
Home History
| Club Friendly List | 2021/09/09 18:30 | Sevilla v CD Alaves | W | 1-0 |
| Spain La Liga | 2021/08/28 17:30 | Elche v Sevilla | D | 1-1 |
| Spain La Liga | 2021/08/23 18:00 | Getafe v Sevilla | W | 0-1 |
| Spain La Liga | 2021/08/15 20:15 | Sevilla v Rayo Vallecano | W | 3-0 |
| Elite Club Friendlies | 2021/07/31 16:30 | Roma v Sevilla | D | 0-0 |
| Elite Club Friendlies | 2021/07/27 18:00 | Sevilla v PSG | D | 2-2 |
| Europe Friendlies | 2021/07/22 17:00 | Sevilla v Las Palmas | W | 1-0 |
| Europe Friendlies | 2021/07/17 17:00 | Sevilla v Coventry | W | 4-0 |
Away History
| Europe Friendlies | 2021/09/03 18:00 | Villarreal v Braga | L | 2-3 |
| Spain La Liga | 2021/08/29 20:00 | Atletico Madrid v Villarreal | D | 2-2 |
| Spain La Liga | 2021/08/21 17:30 | Espanyol v Villarreal | D | 0-0 |
| Spain La Liga | 2021/08/16 18:00 | Villarreal v Granada | D | 0-0 |
| UEFA Super Cup | 2021/08/11 19:00 | Chelsea v Villarreal | L | 7-6 |
| Elite Club Friendlies | 2021/08/07 18:00 | Leeds v Villarreal | D | 2-2 |
| Elite Club Friendlies | 2021/08/04 18:45 | Leicester v Villarreal | L | 3-2 |
| Elite Club Friendlies | 2021/07/31 19:00 | Marseille v Villarreal | L | 2-1 |