Benfica 2-0 Spartak Moscow 2021-05-21 13:00
Stadium: Estadio do Sport Lisboa e Benfica Round: 16
Referee: Anthony Taylor Home Manager: Jorge Jesus Away Manager: Rui Vitoria
Home History
| Portugal Primeira Liga | 2021/05/19 19:00 | Guimaraes v Benfica | W | 1-3 |
| Portugal Primeira Liga | 2021/05/15 17:00 | Benfica v Sporting | W | 4-3 |
| Portugal Primeira Liga | 2021/05/11 17:00 | Nacional v Benfica | W | 1-3 |
| Portugal Primeira Liga | 2021/05/06 17:30 | Benfica v FC Porto | D | 1-1 |
| Portugal Primeira Liga | 2021/04/30 18:00 | Tondela v Benfica | W | 0-2 |
| Portugal Primeira Liga | 2021/04/26 18:00 | Benfica v Santa Clara | W | 2-1 |
| Portugal Primeira Liga | 2021/04/22 18:00 | Portimonense v Benfica | W | 1-5 |
| Portugal Primeira Liga | 2021/04/17 17:00 | Benfica v Gil Vicente | L | 1-2 |
Away History
| Russia Premier League | 2021/05/16 11:00 | FC Akhmat Grozny v Spartak Moscow | D | 2-2 |
| Russia Premier League | 2021/05/10 16:00 | Spartak Moscow v FK Khimki | W | 2-1 |
| Russia Premier League | 2021/05/03 13:30 | Arsenal Tula v Spartak Moscow | W | 1-2 |
| Russia Premier League | 2021/04/25 13:30 | Spartak Moscow v CSKA Moscow | W | 1-0 |
| Russia Premier League | 2021/04/18 16:00 | Spartak Moscow v FC Ufa | L | 0-3 |
| Russia Premier League | 2021/04/11 16:00 | Lokomotiv Moscow v Spartak Moscow | L | 2-0 |
| Russia Premier League | 2021/04/04 16:00 | Rostov v Spartak Moscow | W | 2-3 |
| Russia Premier League | 2021/03/18 16:00 | Spartak Moscow v Ural | W | 5-1 |