[17] Once Caldas 0-2 Deportes Tolima [3] 2021-07-18 21:00
Stadium: Estadio Palogrande Round: 13
Referee: Keiner Jose Jimenez Salas Home Manager: Eduardo Lara Lozano Away Manager: Hernan Torres
Head to Head
| Colombia Primera A | 2021/01/18 20:30 | Deportes Tolima v Once Caldas | D | 1-1 |
| Colombia Primera A | 2020/11/15 23:00 | Deportes Tolima v Once Caldas | W | 2-3 |
| Colombia Primera A | 2019/08/18 00:45 | Deportes Tolima v Once Caldas | D | 0-0 |
| Colombia Primera A | 2019/02/24 22:30 | Once Caldas v Deportes Tolima | W | 2-1 |
| Colombia Primera A | 2018/11/08 00:30 | Deportes Tolima v Once Caldas | L | 3-0 |
| Colombia Play-Offs | 2018/05/20 22:15 | Deportes Tolima v Once Caldas | L | 3-0 |
| Colombia Play-Offs | 2018/05/14 00:30 | Once Caldas v Deportes Tolima | W | 1-0 |
| Colombia Primera A | 2018/04/11 23:00 | Once Caldas v Deportes Tolima | L | 0-1 |
Home History
| Colombia Primera A | 2021/04/18 21:30 | Once Caldas v Independiente Medellin | W | 2-0 |
| Colombia Primera A | 2021/04/14 01:00 | Patriotas FC v Once Caldas | D | 1-1 |
| Colombia Primera A | 2021/04/06 01:00 | Once Caldas v Jaguares de Cordoba | L | 1-2 |
| Colombia Primera A | 2021/04/01 01:00 | Aguilas Doradas v Once Caldas | D | 2-2 |
| Colombia Primera A | 2021/03/27 21:00 | Once Caldas v Boyaca Chico | W | 4-2 |
| Colombia Primera A | 2021/03/24 01:00 | Independiente Santa Fe v Once Caldas | L | 2-0 |
| Colombia Primera A | 2021/03/21 01:00 | Once Caldas v America de Cali | D | 1-1 |
| Colombia Primera A | 2021/03/16 01:00 | Atletico Bucaramanga v Once Caldas | D | 1-1 |
Away History
| Colombia Primera A | 2021/06/20 20:00 | Millonarios v Deportes Tolima | W | 1-2 |
| Colombia Primera A | 2021/06/18 01:00 | Deportes Tolima v Millonarios | D | 1-1 |
| Colombia Primera A | 2021/06/15 00:00 | La Equidad v Deportes Tolima | W | 1-2 |
| Colombia Primera A | 2021/06/10 23:05 | Deportes Tolima v La Equidad | D | 1-1 |
| Colombia Primera A | 2021/06/04 20:30 | Deportivo Cali v Deportes Tolima | L | 2-0 |
| Copa Sudamericana | 2021/05/26 00:30 | Deportes Tolima v Bragantino | L | 1-2 |
| Copa Sudamericana | 2021/05/19 22:15 | Emelec v Deportes Tolima | L | 2-0 |
| Copa Sudamericana | 2021/05/12 00:30 | CA Talleres de Córdoba v Deportes Tolima | D | 0-0 |