Home History
| Germany Bundesliga II Women | 2021/11/21 10:00 | Nurnberg (W) v RB Leipzig (W) | L | 4-3 |
| Germany Bundesliga II Women | 2021/11/07 10:00 | RB Leipzig (W) v Elversberg Women | W | 3-0 |
| Germany Bundesliga II Women | 2021/10/17 09:00 | BV Borussia Bocholt Women v RB Leipzig (W) | W | 1-9 |
| Germany Bundesliga II Women | 2021/10/10 09:00 | RB Leipzig (W) v SG Andernach Women | L | 0-1 |
| Germany Bundesliga II Women | 2021/10/03 09:00 | SV Meppen Women v RB Leipzig (W) | L | 5-0 |
| Germany DFB Pokal Women | 2021/09/26 12:00 | RB Leipzig (W) v Bayer Leverkusen (W) | L | 1-3 |
| Germany Bundesliga II Women | 2021/09/12 09:00 | RB Leipzig (W) v Eintracht Frankfurt II Women | W | 4-0 |
| Germany Bundesliga II Women | 2021/09/05 09:00 | Bayern Munich II Women v RB Leipzig (W) | L | 3-1 |
Away History
| Germany Bundesliga II Women | 2021/11/14 10:00 | Elversberg Women v MSV Duisburg Women | W | 1-5 |
| Germany Bundesliga II Women | 2021/11/07 13:00 | MSV Duisburg Women v BV Borussia Bocholt Women | W | 3-0 |
| Germany Bundesliga II Women | 2021/10/17 12:00 | SG Andernach Women v MSV Duisburg Women | L | 3-1 |
| Germany Bundesliga II Women | 2021/10/10 12:00 | MSV Duisburg Women v SV Meppen Women | W | 3-0 |
| Germany Bundesliga II Women | 2021/10/03 09:00 | Eintracht Frankfurt II Women v MSV Duisburg Women | W | 1-3 |
| Germany DFB Pokal Women | 2021/09/27 16:30 | MSV Duisburg Women v Wolfsburg (W) | L | 1-3 |
| Germany Bundesliga II Women | 2021/09/12 09:00 | MSV Duisburg Women v Bayern Munich II Women | W | 2-1 |
| Germany Bundesliga II Women | 2021/09/05 09:00 | TSG 1899 Hoffenheim II Women v MSV Duisburg Women | L | 1-0 |