[28] Karen Khachanov 3-6,2-6 Stefanos Tsitsipas [3] 2021-04-03 09:00
Stadium: Stadium Round: 26 Ground: Hardcourt outdoor
Head to Head
| ATP Rotterdam | 2021/03/05 12:00 | Karen Khachanov v Stefanos Tsitsipas | 6-4,3-6,5-7 |
| Boodles Challenge | 2019/06/26 15:05 | Stefanos Tsitsipas v Karen Khachanov | 6-3,3-6,8-10 |
| ATP Shanghai | 2018/10/10 06:40 | Karen Khachanov v Stefanos Tsitsipas | 4-6,6-7 |
| ATP Shanghai | 2017/10/09 07:40 | Stefanos Tsitsipas v Karen Khachanov | 7-5,6-3 |
Home History
| ATP Miami | 2021/03/28 17:10 | Jannik Sinner v Karen Khachanov | 4-6,7-6,6-4 |
| ATP Miami | 2021/03/26 19:10 | Yannick Hanfmann v Karen Khachanov | 3-6,2-6 |
| ATP Dubai | 2021/03/17 10:00 | Jeremy Chardy v Karen Khachanov | 6-7,6-4,6-4 |
| ATP Dubai | 2021/03/16 10:25 | Alexei Popyrin v Karen Khachanov | 4-6,6-3,6-7 |
| ATP Marseille | 2021/03/12 13:30 | Karen Khachanov v Matthew Ebden | 6-4,4-6,2-6 |
| ATP Marseille | 2021/03/10 15:10 | Karen Khachanov v Mackenzie McDonald | 7-6,6-4 |
| ATP Rotterdam | 2021/03/05 12:00 | Karen Khachanov v Stefanos Tsitsipas | 6-4,3-6,5-7 |
| ATP Rotterdam | 2021/03/03 20:25 | Karen Khachanov v Cameron Norrie | 6-2,6-2 |
Away History
| ATP Miami | 2021/04/01 17:00 | Hubert Hurkacz v Stefanos Tsitsipas | 2-6,6-3,6-4 |
| ATP Miami | 2021/03/31 01:05 | Lorenzo Sonego v Stefanos Tsitsipas | 2-6,6-7 |
| ATP Miami | 2021/03/29 23:00 | Kei Nishikori v Stefanos Tsitsipas | 3-6,6-3,1-6 |
| ATP Miami | 2021/03/27 16:25 | Damir Dzumhur v Stefanos Tsitsipas | 1-6,4-6 |
| ATP Acapulco | 2021/03/21 03:00 | Stefanos Tsitsipas v Alexander Zverev | 4-6,6-7 |
| ATP Acapulco | 2021/03/20 04:25 | Stefanos Tsitsipas v Lorenzo Musetti | 6-1,6-3 |
| ATP Acapulco | 2021/03/19 02:10 | Stefanos Tsitsipas v Felix Auger Aliassime | 7-5,4-6,6-3 |
| ATP Acapulco | 2021/03/18 04:00 | Stefanos Tsitsipas v John Isner | 6-3,6-2 |