SE Missouri State 30-14 Austin Peay 2021-08-07 12:00
Stadium: Fortera Stadium Round: 1
Home Manager: Tom Matukewicz Away Manager: Marquase Lovings
Head to Head
| NCAAF | 2021/03/14 19:00 | Austin Peay v SE Missouri St | L | 49-42 |
| NCAAF | 2019/10/12 19:00 | SE Missouri St v Austin Peay | L | 24-28 |
| NCAAF | 2018/10/13 18:00 | Austin Peay v SE Missouri St | W | 27-31 |
| NCAAF | 2017/10/21 21:00 | Austin Peay v SE Missouri St | L | 38-31 |
Home History
| NCAAF | 2021/04/11 19:30 | SE Missouri St v Tennessee State | W | 46-23 |
| NCAAF | 2021/04/03 18:00 | SE Missouri St v Tennessee Martin | W | 21-16 |
| NCAAF | 2021/03/28 19:00 | Tennessee Tech v SE Missouri St | W | 21-24 |
| NCAAF | 2021/03/21 19:00 | SE Missouri St v Jacksonville State | L | 3-21 |
| NCAAF | 2021/03/14 19:00 | Austin Peay v SE Missouri St | L | 49-42 |
| NCAAF | 2021/03/07 20:00 | Murray State v SE Missouri St | L | 24-21 |
| NCAAF | 2021/02/28 20:00 | Eastern Illinois v SE Missouri St | W | 7-47 |
| NCAAF | 2020/10/30 23:00 | SE Missouri St v SO Illinois | L | 17-20 |
Away History
| NCAAF | 2021/04/03 19:00 | Murray State v Austin Peay | W | 31-34 |
| NCAAF | 2021/03/28 19:00 | Austin Peay v Jacksonville State | W | 13-10 |
| NCAAF | 2021/03/21 19:00 | Tennessee Martin v Austin Peay | L | 37-34 |
| NCAAF | 2021/03/14 19:00 | Austin Peay v SE Missouri St | W | 49-42 |
| NCAAF | 2021/02/28 20:00 | Tennessee State v Austin Peay | W | 20-27 |
| NCAAF | 2021/02/21 19:30 | Austin Peay v Tennessee Tech | L | 21-27 |
| NCAAF | 2020/09/19 16:00 | Austin Peay v Cincinnati | L | 20-55 |
| NCAAF | 2020/09/12 20:00 | Austin Peay v Pittsburgh | L | 0-55 |