[12] UL Lafayette 42-14 Liberty [31] 2021-09-13 13:00
Stadium: Williams Stadium Round: 1
Home Manager: Billy Napier Away Manager: Hugh Freeze
Home History
| NCAAF | 2021/09/11 23:00 | Nicholls State v Lafayette | W | 24-27 |
| NCAAF | 2021/09/11 22:00 | Lafayette v William & Mary | L | 3-24 |
| NCAAF | 2021/09/04 20:30 | Lafayette v Texas | L | 18-38 |
| NCAAF | 2021/09/04 18:00 | Lafayette v Air Force | L | 14-35 |
| NCAAF | 2021/04/10 16:30 | Lehigh v Lafayette | W | 13-20 |
| NCAAF | 2021/03/27 20:00 | Lafayette v Bucknell | L | 13-38 |
| NCAAF | 2021/03/13 20:30 | Colgate v Lafayette | W | 10-24 |
| NCAAF | 2020/12/26 20:30 | Lafayette v Texas-San Antonio | W | 31-24 |
Away History
| NCAAF | 2021/09/11 23:00 | Liberty v Troy | W | 21-13 |
| NCAAF | 2021/09/04 22:00 | Campbell v Liberty | W | 7-48 |
| NCAAF | 2020/12/27 00:30 | Liberty v Coastal Carolina | W | 37-34 |
| NCAAF | 2020/11/27 17:00 | Massachusetts v Liberty | W | 0-45 |
| NCAAF | 2020/11/22 00:30 | Liberty v NC State | L | 14-15 |
| NCAAF | 2020/11/14 17:00 | Western Carolina v Liberty | W | 14-58 |
| NCAAF | 2020/11/07 17:00 | Liberty v Virginia Tech | W | 38-35 |
| NCAAF | 2020/10/24 17:00 | Southern Mississippi v Liberty | W | 35-56 |