[29] Appalachian State 13-41 UL Lafayette [34] 2021-08-03 23:30
Stadium: Cajun Field at Our Lady of Lourdes Stadium Round: 1
Home Manager: Billy Napier Away Manager: Shawn Clark
Head to Head
| NCAAF | 2020/12/05 01:30 | Lafayette v Appalachian St | L | 24-21 |
| NCAAF | 2019/12/07 17:00 | Lafayette v Appalachian St | W | 38-45 |
| NCAAF | 2019/10/10 00:00 | Appalachian St v Lafayette | W | 17-7 |
| NCAAF | 2018/12/01 17:00 | Lafayette v Appalachian St | W | 19-30 |
| NCAAF | 2018/10/20 19:30 | Lafayette v Appalachian St | W | 17-27 |
| NCAAF | 2017/12/02 19:30 | Lafayette v Appalachian St | W | 14-63 |
| NCAAF | 2016/10/13 00:00 | Appalachian St v Lafayette | W | 24-0 |
| NCAAF | 2015/11/28 19:00 | Appalachian St v Lafayette | W | 28-7 |
Home History
| NCAAF | 2020/12/21 19:30 | North Texas v Appalachian St | W | 28-56 |
| NCAAF | 2020/12/12 23:00 | Appalachian St v Georgia Southern | W | 34-26 |
| NCAAF | 2020/12/05 01:30 | Lafayette v Appalachian St | L | 24-21 |
| NCAAF | 2020/11/28 20:30 | Troy v Appalachian St | W | 10-47 |
| NCAAF | 2020/11/21 17:00 | Appalachian St v Coastal Carolina | L | 23-34 |
| NCAAF | 2020/11/14 19:30 | Georgia State v Appalachian St | W | 13-17 |
| NCAAF | 2020/11/07 20:00 | Appalachian St v Texas State | W | 38-17 |
| NCAAF | 2020/10/31 20:00 | Appalachian St v UL Monroe | W | 31-13 |
Away History
| NCAAF | 2021/04/10 16:30 | Lehigh v Lafayette | W | 13-20 |
| NCAAF | 2021/03/27 20:00 | Lafayette v Bucknell | L | 13-38 |
| NCAAF | 2021/03/13 20:30 | Colgate v Lafayette | W | 10-24 |
| NCAAF | 2020/12/26 20:30 | Lafayette v Texas-San Antonio | W | 31-24 |
| NCAAF | 2020/12/05 01:30 | Lafayette v Appalachian St | W | 24-21 |
| NCAAF | 2020/11/28 20:00 | Lafayette v UL Monroe | W | 70-20 |
| NCAAF | 2020/11/14 19:00 | South Alabama v Lafayette | W | 10-38 |
| NCAAF | 2020/11/07 17:00 | Arkansas State v Lafayette | W | 20-27 |