[2] Ghana 1-0 South Africa [1] 2021-07-04 01:00
Round: 1
Home Manager: Charles Kwablan Akonnor Away Manager: Hugo Broos
Head to Head
| Africa Cup of Nations Qualification | 2021/03/25 16:00 | South Africa v Ghana | D | 1-1 |
| Africa Cup of Nations Qualification | 2019/11/14 19:00 | Ghana v South Africa | W | 2-0 |
| International Match | 2019/06/15 13:30 | Ghana v South Africa | D | 0-0 |
| International Match | 2016/10/11 17:00 | South Africa v Ghana | D | 1-1 |
| Africa Cup of Nations | 2015/01/27 18:00 | South Africa v Ghana | W | 1-2 |
Home History
| International Match | 2021/06/12 17:00 | Ghana v Ivory Coast | D | 0-0 |
| International Match | 2021/06/08 19:00 | Morocco v Ghana | L | 1-0 |
| Africa Cup of Nations Qualification | 2021/03/28 16:00 | Ghana v Sao Tome e Principe | W | 3-1 |
| Africa Cup of Nations Qualification | 2021/03/25 16:00 | South Africa v Ghana | D | 1-1 |
| Africa Cup of Nations Qualification | 2020/11/17 13:00 | Sudan v Ghana | L | 1-0 |
| Africa Cup of Nations Qualification | 2020/11/12 16:00 | Ghana v Sudan | W | 2-0 |
| International Match | 2020/10/12 15:30 | Ghana v Qatar | W | 5-1 |
| International Match | 2020/10/09 17:00 | Ghana v Mali | L | 0-3 |
Away History
| International Match | 2021/06/10 16:00 | South Africa v Uganda | W | 3-2 |
| Africa Cup of Nations Qualification | 2021/03/28 16:00 | Sudan v South Africa | L | 2-0 |
| Africa Cup of Nations Qualification | 2021/03/25 16:00 | South Africa v Ghana | D | 1-1 |
| Africa Cup of Nations Qualification | 2020/11/16 13:00 | South Africa v Sao Tome e Principe | W | 4-2 |
| Africa Cup of Nations Qualification | 2020/11/13 19:00 | South Africa v Sao Tome e Principe | W | 2-0 |
| International Match | 2020/10/11 13:00 | South Africa v Zambia | L | 1-2 |
| International Match | 2020/10/08 16:00 | South Africa v Namibia | D | 1-1 |
| Africa Cup of Nations Qualification | 2019/11/17 13:00 | South Africa v Sudan | W | 1-0 |