London Irish 22-42 Northampton 2021-11-07 21:00
Stadium: Brentford Community Stadium Round: 21
Referee: Wayne Barnes
Head to Head
| Prem Rugby | 2021/10/02 13:00 | Northampton v London Irish | L | 23-21 |
| Prem Rugby | 2021/04/16 18:45 | Northampton v London Irish | L | 44-26 |
| Prem Rugby | 2020/08/22 13:00 | London Irish v Northampton | L | 3-27 |
| Prem Rugby | 2020/01/24 19:45 | Northampton v London Irish | W | 16-20 |
| Prem Rugby | 2018/02/17 15:00 | Northampton v London Irish | L | 25-17 |
| Prem Rugby | 2017/09/24 14:00 | London Irish v Northampton | L | 25-40 |
| Prem Rugby | 2016/02/13 15:00 | Northampton v London Irish | L | 35-7 |
| Prem Rugby | 2015/12/26 14:30 | London Irish v Northampton | W | 25-23 |
Home History
| Prem Rugby | 2021/11/06 15:00 | Saracens v London Irish | D | 34-34 |
| Prem Rugby | 2021/10/30 14:00 | London Irish v Bristol | L | 33-45 |
| Prem Rugby | 2021/10/23 14:00 | Exeter Chiefs v London Irish | W | 21-33 |
| Prem Rugby | 2021/10/17 14:00 | London Irish v Gloucester | D | 25-25 |
| Prem Rugby | 2021/10/09 14:00 | London Irish v Leicester | L | 16-21 |
| Prem Rugby | 2021/10/02 13:00 | Northampton v London Irish | L | 23-21 |
| Prem Rugby | 2021/09/26 14:00 | London Irish v Sale Sharks | D | 31-31 |
| Prem Rugby | 2021/09/18 14:00 | Worcester Warriors v London Irish | L | 36-24 |
Away History
| Prem Rugby | 2021/11/06 17:00 | Sale Sharks v Northampton | L | 30-6 |
| Prem Rugby | 2021/10/30 14:00 | Northampton v Leicester | L | 26-55 |
| Prem Rugby | 2021/10/22 18:45 | Northampton v Worcester Warriors | W | 66-10 |
| Prem Rugby | 2021/10/10 14:00 | Wasps v Northampton | L | 26-20 |
| Prem Rugby | 2021/10/02 13:00 | Northampton v London Irish | W | 23-21 |
| Prem Rugby | 2021/09/25 14:00 | Exeter Chiefs v Northampton | W | 24-26 |
| Prem Rugby | 2021/09/18 14:00 | Northampton v Gloucester | W | 34-20 |
| Prem Rugby | 2021/06/12 14:00 | Bath v Northampton | L | 30-24 |