[27] Reilly Opelka 4-6,2-6 Jannik Sinner [11] 2021-08-02 06:00
Stadium: Center Court Round: 25 Ground: Hardcourt indoor
Home History
| ATP Atlanta | 2021/07/30 18:10 | Taylor Fritz v Reilly Opelka | 7-6,6-7,7-6 |
| ATP Atlanta | 2021/07/29 01:30 | Bjorn Fratangelo v Reilly Opelka | 6-7,6-7 |
| Wimbledon | 2021/06/28 16:15 | Reilly Opelka v Dominik Koepfer | 4-6,6-7,2-6 |
| ATP Queens | 2021/06/14 11:30 | Reilly Opelka v John Millman | 6-7,7-5,6-7 |
| French Open | 2021/06/04 13:40 | Reilly Opelka v Daniil Medvedev | 4-6,2-6,4-6 |
| French Open | 2021/06/02 13:45 | Reilly Opelka v Jaume Munar | 6-3,6-2,3-6,7-5 |
| French Open | 2021/05/31 12:15 | Reilly Opelka v Andrej Martin | 6-3,6-2,6-4 |
| ATP Geneva | 2021/05/18 11:10 | Pablo Cuevas v Reilly Opelka | 7-6,6-2 |
Away History
| ATP Atlanta | 2021/07/29 17:30 | Christopher O'Connell v Jannik Sinner | 7-6,6-4 |
| Wimbledon | 2021/06/28 14:30 | Marton Fucsovics v Jannik Sinner | 5-7,6-3,7-5,6-3 |
| ATP Queens | 2021/06/14 11:00 | Jack Draper v Jannik Sinner | 7-6,7-6 |
| French Open | 2021/06/07 15:25 | Rafael Nadal v Jannik Sinner | 7-5,6-3,6-0 |
| French Open | 2021/06/05 11:30 | Jannik Sinner v Mikael Ymer | 6-1,7-5,6-3 |
| French Open | 2021/06/03 11:15 | Jannik Sinner v Gianluca Mager | 6-1,7-5,3-6,6-3 |
| French Open | 2021/05/31 09:00 | Jannik Sinner v Pierre-Hugues Herbert | 6-1,4-6,6-7,7-5,6-4 |
| ATP Lyon | 2021/05/20 15:55 | Arthur Rinderknech v Jannik Sinner | 6-7,6-2,7-5 |