Stadium: Credit Union 1 Arena
Home Manager: Lisa Stone Away Manager: Tasha Pointer
| WNCAAB | 2021/03/23 00:00 | Northern Iowa (W) v Saint Louis (W) | L | 58-50 |
| WNCAAB | 2021/03/21 01:00 | Saint Louis (W) v Wisc Milwaukee (W) | W | 61-44 |
| WNCAAB | 2021/03/19 22:00 | Saint Louis (W) v DePaul (W) | W | 74-72 |
| WNCAAB | 2021/03/13 21:00 | Massachusetts (W) v Saint Louis (W) | L | 90-81 |
| WNCAAB | 2021/03/13 01:00 | Richmond (W) v Saint Louis (W) | W | 58-59 |
| WNCAAB | 2021/02/26 22:00 | Saint Louis (W) v Davidson Women | W | 57-45 |
| WNCAAB | 2021/02/20 19:00 | Dayton (W) v Saint Louis (W) | W | 57-64 |
| WNCAAB | 2021/02/14 20:00 | Richmond (W) v Saint Louis (W) | W | 57-62 |
| WNCAAB | 2021/02/26 00:00 | Cleveland State Women v Illinois Chicago (W) | L | 69-43 |
| WNCAAB | 2021/02/20 20:00 | Illinois Chicago (W) v Wisc Milwaukee (W) | L | 53-72 |
| WNCAAB | 2021/02/19 20:00 | Wisc Milwaukee (W) v Illinois Chicago (W) | L | 58-35 |
| WNCAAB | 2021/02/13 17:00 | Wisc Green Bay (W) v Illinois Chicago (W) | L | 70-45 |
| WNCAAB | 2021/02/12 17:00 | Illinois Chicago (W) v Wisc Green Bay (W) | L | 56-80 |
| WNCAAB | 2021/02/06 20:00 | Illinois Chicago (W) v IU Indianapolis Women | L | 64-74 |
| WNCAAB | 2021/02/05 20:00 | IU Indianapolis Women v Illinois Chicago (W) | L | 71-52 |
| WNCAAB | 2021/01/23 19:00 | Youngstown State (W) v Illinois Chicago (W) | L | 71-55 |