Stadium: Alumni Coliseum McBrayer Arena
Home Manager: Tony Pujol Away Manager: A.W. Hamilton
| NCAAB | 2021/12/18 20:00 | North Alabama v Southeastern Baptist Chargers | W | 106-40 |
| NCAAB | 2021/12/15 02:00 | North Alabama v Auburn | L | 44-70 |
| NCAAB | 2021/12/09 00:00 | Alabama A&M v North Alabama | W | 45-56 |
| NCAAB | 2021/12/05 20:00 | North Alabama v Carver | W | 103-40 |
| NCAAB | 2021/12/02 02:00 | Mississippi Valley State v North Alabama | W | 58-72 |
| NCAAB | 2021/11/28 20:30 | North Alabama v Alabama State | W | 81-69 |
| NCAAB | 2021/11/24 02:00 | North Alabama v Oakwood | W | 105-50 |
| NCAAB | 2021/11/21 01:30 | Iona v North Alabama | L | 81-65 |
| NCAAB | 2021/12/19 00:00 | Northern Kentucky v Eastern Kentucky | W | 68-81 |
| NCAAB | 2021/12/16 00:00 | Eastern Kentucky v Midway | W | 121-67 |
| NCAAB | 2021/12/12 00:00 | Marshall v Eastern Kentucky | L | 80-69 |
| NCAAB | 2021/12/08 03:00 | Eastern Kentucky v USC Trojans | L | 68-80 |
| NCAAB | 2021/12/05 00:00 | Eastern Kentucky v Western Kentucky | L | 80-85 |
| NCAAB | 2021/11/28 21:30 | Eastern Kentucky v Radford | L | 75-88 |
| NCAAB | 2021/11/27 00:00 | Eastern Kentucky v West Virginia | L | 77-80 |
| NCAAB | 2021/11/23 00:00 | Eastern Illinois v Eastern Kentucky | W | 43-82 |