Stadium: The Buc Dome
Home Manager: Clarisse Garcia Away Manager:
| WNCAAB | 2021/11/16 23:00 | George Mason (W) v Charleston Southern (W) | L | 64-55 |
| WNCAAB | 2021/11/09 23:00 | Charleston Southern (W) v Alabama (W) | L | 32-109 |
| WNCAAB | 2021/03/06 19:00 | USC Upstate (W) v Charleston Southern (W) | L | 72-64 |
| WNCAAB | 2021/02/21 18:00 | Charleston Southern (W) v Radford (W) | L | 67-76 |
| WNCAAB | 2021/02/20 19:00 | Radford (W) v Charleston Southern (W) | L | 74-73 |
| WNCAAB | 2021/02/13 20:00 | Longwood (W) v Charleston Southern (W) | L | 76-51 |
| WNCAAB | 2021/02/13 00:00 | Longwood (W) v Charleston Southern (W) | L | 94-48 |
| WNCAAB | 2021/02/06 23:00 | Charleston Southern (W) v High Point (W) | L | 54-71 |
| WNCAAB | 2021/11/10 00:00 | Liberty (W) v Belmont Abbey Women | L | 89-40 |
| WNCAAB | 2020/12/04 23:00 | UNC Greensboro (W) v Belmont Abbey Women | W | 60-63 |