St George/Illawarra Dragons 16-20 Penrith Panthers 2021-10-17 05:00
Head to Head
| NRL | 2021/08/13 08:00 | St George/Illawarra Dragons v Penrith Panthers | L | 16-34 |
| NRL | 2020/03/20 07:00 | St George/Illawarra Dragons v Penrith Panthers | L | 28-32 |
| NRL | 2019/07/19 09:55 | Penrith Panthers v St George/Illawarra Dragons | L | 40-18 |
| NRL | 2018/05/26 09:35 | Penrith Panthers v St George/Illawarra Dragons | L | 28-2 |
| NRL | 2017/08/27 06:00 | Penrith Panthers v St George/Illawarra Dragons | W | 14-16 |
| NRL | 2017/03/04 05:30 | St George/Illawarra Dragons v Penrith Panthers | W | 42-10 |
| NRL | 2016/03/27 05:00 | St George/Illawarra Dragons v Penrith Panthers | W | 14-12 |
| NRL | 2015/08/20 09:45 | St George/Illawarra Dragons v Penrith Panthers | W | 19-12 |
Home History
| NRL | 2021/09/04 09:35 | South Sydney Rabbitohs v St George/Illawarra Dragons | L | 20-16 |
| NRL | 2021/08/28 05:00 | St George/Illawarra Dragons v North Queensland Cowboys | L | 26-38 |
| NRL | 2021/08/22 04:00 | St George/Illawarra Dragons v Sydney Roosters | L | 22-40 |
| NRL | 2021/08/13 08:00 | St George/Illawarra Dragons v Penrith Panthers | L | 16-34 |
| NRL | 2021/08/06 08:00 | Canberra Raiders v St George/Illawarra Dragons | L | 20-12 |
| NRL | 2021/08/01 08:25 | St George/Illawarra Dragons v South Sydney Rabbitohs | L | 14-50 |
| NRL | 2021/07/25 03:50 | St George/Illawarra Dragons v Gold Coast Titans | L | 10-32 |
| NRL | 2021/07/16 10:05 | Manly Sea Eagles v St George/Illawarra Dragons | L | 32-18 |
Away History
| NRL | 2021/10/03 08:30 | Penrith Panthers v South Sydney Rabbitohs | W | 14-12 |
| NRL | 2021/09/25 06:00 | Melbourne Storm v Penrith Panthers | W | 6-10 |
| NRL | 2021/09/18 09:50 | Penrith Panthers v Parramatta Eels | W | 8-6 |
| NRL | 2021/09/11 09:50 | Penrith Panthers v South Sydney Rabbitohs | L | 10-16 |
| NRL | 2021/09/03 10:05 | Parramatta Eels v Penrith Panthers | W | 6-40 |
| NRL | 2021/08/29 06:05 | Penrith Panthers v Wests Tigers | W | 30-16 |
| NRL | 2021/08/20 10:05 | Penrith Panthers v South Sydney Rabbitohs | W | 25-12 |
| NRL | 2021/08/13 08:00 | St George/Illawarra Dragons v Penrith Panthers | W | 16-34 |