[12] Sliema Wanderers 1-0 Sirens [5] 2022-01-20 01:00
Stadium: Ta' Qali National Stadium Round: 16
Home Manager: Andrea Pisanu Away Manager: Steve D'Amato
Head to Head
| Malta Premier League | 2021/09/26 17:00 | Sirens v Sliema Wanderers | D | 2-2 |
| Malta Premier League | 2021/01/23 17:00 | Sliema Wanderers v Sirens | L | 1-3 |
| Malta Premier League | 2020/09/25 19:15 | Sirens v Sliema Wanderers | D | 0-0 |
| Malta Premier League | 2020/02/21 17:00 | Sirens v Sliema Wanderers | D | 0-0 |
| Malta Premier League | 2019/10/05 15:15 | Sliema Wanderers v Sirens | L | 0-1 |
Home History
| Malta Premier League | 2022/01/18 16:00 | Sliema Wanderers v Gzira United | L | 1-3 |
| Malta Premier League | 2021/12/19 13:00 | Floriana v Sliema Wanderers | L | 2-0 |
| Malta Premier League | 2021/12/05 10:30 | Sliema Wanderers v Hamrun Spartans | L | 0-2 |
| Malta Premier League | 2021/11/27 15:00 | Birkirkara v Sliema Wanderers | L | 2-0 |
| Malta Premier League | 2021/11/20 15:00 | Sliema Wanderers v Valletta | W | 2-1 |
| Malta Premier League | 2021/10/31 18:00 | Sliema Wanderers v Mosta FC | L | 2-3 |
| Malta Premier League | 2021/10/24 13:00 | Santa Lucia FC v Sliema Wanderers | D | 0-0 |
| Malta Premier League | 2021/10/17 13:00 | Sliema Wanderers v Hibernians | L | 0-3 |
Away History
| Malta Premier League | 2022/01/18 18:00 | Hibernians v Sirens | D | 1-1 |
| Malta Premier League | 2021/12/18 17:00 | Mosta FC v Sirens | W | 2-3 |
| Malta Premier League | 2021/12/13 13:00 | Sirens v Gudja United | D | 0-0 |
| Malta Premier League | 2021/12/04 17:00 | Sirens v Gzira United | L | 1-3 |
| Malta Premier League | 2021/11/27 13:00 | Floriana v Sirens | W | 1-2 |
| Malta Premier League | 2021/11/21 13:00 | Sirens v Balzan FC | L | 1-6 |
| Malta Premier League | 2021/10/30 17:00 | Hamrun Spartans v Sirens | L | 1-0 |
| Malta Premier League | 2021/10/24 17:00 | Sirens v Birkirkara | W | 3-2 |