CF Montreal 3-0 Santos Laguna 2021-12-11 21:15
Stadium: Saputo Stadium Round: 4
Referee: Juan Gabriel Calderon Perez Home Manager: Wilfried Nancy Away Manager: Pedro Caixinha
Home History
| Canada Championships | 2021/11/21 18:00 | CF Montreal v Toronto FC | W | 1-0 |
| USA MLS | 2021/11/07 20:30 | CF Montreal v Orlando City SC | L | 0-2 |
| USA MLS | 2021/11/03 23:30 | CF Montreal v Houston Dynamo | W | 2-0 |
| USA MLS | 2021/10/30 20:00 | New York Red Bulls v CF Montreal | L | 1-0 |
| Canada Championships | 2021/10/27 23:30 | Forge FC v CF Montreal | W | 7-8 |
| USA MLS | 2021/10/23 23:30 | Toronto FC v CF Montreal | D | 1-1 |
| USA MLS | 2021/10/20 23:30 | Orlando City SC v CF Montreal | D | 1-1 |
| USA MLS | 2021/10/16 17:00 | CF Montreal v Philadelphia Union | D | 2-2 |
Away History
| Mexico Liga MX | 2021/11/29 00:00 | Tigres UANL v Santos Laguna | L | 1-0 |
| Mexico Liga MX | 2021/11/26 03:05 | Santos Laguna v Tigres UANL | W | 2-1 |
| Mexico Liga MX | 2021/11/21 01:00 | Santos Laguna v Atletico San Luis | W | 2-0 |
| Mexico Liga MX | 2021/11/08 01:06 | Santos Laguna v Atletico San Luis | D | 0-0 |
| Mexico Liga MX | 2021/11/05 01:00 | Unam Pumas v Santos Laguna | W | 0-3 |
| Mexico Liga MX | 2021/10/30 22:00 | Queretaro v Santos Laguna | W | 2-3 |
| Mexico Liga MX | 2021/10/25 00:06 | Santos Laguna v Toluca | D | 2-2 |
| Mexico Liga MX | 2021/10/20 00:05 | Club America v Santos Laguna | L | 2-1 |