[3] Cartagines 4-1 Santos de Guápiles [10] 2022-04-02 10:00
Stadium: Jose Rafael Fello Meza Ivankovich Round: 19
Head to Head
| Costa Rica Primera Division | 2022/02/28 00:00 | Santos de Guápiles v Cartagines | W | 1-3 |
| Costa Rica Primera Division | 2021/11/24 23:00 | Santos de Guápiles v Cartagines | W | 1-2 |
| Costa Rica Primera Division | 2021/09/12 02:00 | Cartagines v Santos de Guápiles | L | 1-2 |
| Costa Rica Primera Division | 2021/03/09 01:00 | Santos de Guápiles v Cartagines | L | 1-0 |
| Costa Rica Primera Division | 2021/01/15 02:00 | Cartagines v Santos de Guápiles | W | 1-0 |
| Costa Rica Primera Division | 2020/11/11 17:00 | Cartagines v Santos de Guápiles | W | 3-0 |
| Costa Rica Primera Division | 2020/03/01 21:00 | Santos de Guápiles v Cartagines | W | 1-3 |
| Costa Rica Primera Division | 2020/01/12 17:00 | Cartagines v Santos de Guápiles | D | 2-2 |
Home History
| Costa Rica Primera Division | 2022/04/01 02:30 | Cartagines v ADR Jicaral | D | 0-0 |
| Costa Rica Primera Division | 2022/03/06 21:00 | AD Guanacasteca v Cartagines | D | 1-1 |
| Costa Rica Primera Division | 2022/03/02 02:00 | Cartagines v AD San Carlos | D | 1-1 |
| Costa Rica Primera Division | 2022/02/28 00:00 | Santos de Guápiles v Cartagines | W | 1-3 |
| Costa Rica Primera Division | 2022/02/20 17:00 | Cartagines v Herediano | W | 1-0 |
| Costa Rica Primera Division | 2022/02/13 20:00 | AD Grecia v Cartagines | L | 2-0 |
| Costa Rica Primera Division | 2022/02/10 02:00 | Alajuelense v Cartagines | L | 3-2 |
| Costa Rica Primera Division | 2022/02/04 02:00 | Cartagines v Sporting San Jose | W | 2-1 |
Away History
| Costa Rica Primera Division | 2022/04/02 00:00 | Alajuelense v Santos de Guápiles | W | 0-2 |
| Costa Rica Primera Division | 2022/03/20 23:00 | Santos de Guápiles v Sporting San Jose | L | 2-3 |
| Costa Rica Primera Division | 2022/03/13 01:00 | AD San Carlos v Santos de Guápiles | L | 1-0 |
| Costa Rica Primera Division | 2022/03/05 20:00 | AD Grecia v Santos de Guápiles | L | 2-0 |
| Costa Rica Primera Division | 2022/03/02 23:30 | Santos de Guápiles v AD Guanacasteca | W | 2-0 |
| Costa Rica Primera Division | 2022/02/28 00:00 | Santos de Guápiles v Cartagines | L | 1-3 |
| CONCACAF Champions Cup | 2022/02/23 23:00 | New York City FC v Santos de Guápiles | L | 4-0 |
| Costa Rica Primera Division | 2022/02/19 01:00 | Guadalupe FC v Santos de Guápiles | L | 4-1 |