[12] AD Guanacasteca 2-0 Santos de Guápiles [10] 2022-04-04 23:00
Stadium: Chorotega Stadium Round: 20
Head to Head
| Costa Rica Primera Division | 2022/03/02 23:30 | Santos de Guápiles v AD Guanacasteca | L | 2-0 |
| Costa Rica Primera Division | 2021/10/17 20:00 | AD Guanacasteca v Santos de Guápiles | L | 1-3 |
| Costa Rica Primera Division | 2021/08/14 23:30 | Santos de Guápiles v AD Guanacasteca | L | 2-1 |
Home History
| Costa Rica Primera Division | 2022/04/01 21:00 | AD Guanacasteca v Guadalupe FC | L | 1-2 |
| Costa Rica Primera Division | 2022/03/13 21:00 | AD Guanacasteca v Deportivo Saprissa | L | 1-2 |
| Costa Rica Primera Division | 2022/03/06 21:00 | AD Guanacasteca v Cartagines | D | 1-1 |
| Costa Rica Primera Division | 2022/03/02 23:30 | Santos de Guápiles v AD Guanacasteca | L | 2-0 |
| Costa Rica Primera Division | 2022/02/27 02:00 | Herediano v AD Guanacasteca | W | 1-2 |
| Costa Rica Primera Division | 2022/02/23 21:00 | ADR Jicaral v AD Guanacasteca | D | 2-2 |
| Costa Rica Primera Division | 2022/02/20 21:00 | AD Guanacasteca v Sporting San Jose | W | 2-0 |
| Costa Rica Primera Division | 2022/02/15 01:00 | AD San Carlos v AD Guanacasteca | L | 3-1 |
Away History
| Costa Rica Primera Division | 2022/04/02 00:00 | Alajuelense v Santos de Guápiles | W | 0-2 |
| Costa Rica Primera Division | 2022/03/20 23:00 | Santos de Guápiles v Sporting San Jose | L | 2-3 |
| Costa Rica Primera Division | 2022/03/13 01:00 | AD San Carlos v Santos de Guápiles | L | 1-0 |
| Costa Rica Primera Division | 2022/03/05 20:00 | AD Grecia v Santos de Guápiles | L | 2-0 |
| Costa Rica Primera Division | 2022/03/02 23:30 | Santos de Guápiles v AD Guanacasteca | W | 2-0 |
| Costa Rica Primera Division | 2022/02/28 00:00 | Santos de Guápiles v Cartagines | L | 1-3 |
| CONCACAF Champions Cup | 2022/02/23 23:00 | New York City FC v Santos de Guápiles | L | 4-0 |
| Costa Rica Primera Division | 2022/02/19 01:00 | Guadalupe FC v Santos de Guápiles | L | 4-1 |