2 de Mayo 1-2 River Plate Asuncion 2022-03-19 19:00
Stadium: Estadio Monumental Rio Parapiti Round: 3
Head to Head
| Paraguay Division Intermedia | 2018/09/02 19:00 | 2 de Mayo v River Plate Asuncion | W | 3-1 |
| Paraguay Division Intermedia | 2018/05/26 19:00 | River Plate Asuncion v 2 de Mayo | L | 2-0 |
Home History
| Paraguay Division Intermedia | 2021/10/26 18:30 | 2 de Mayo v Sportivo San Lorenzo | L | 1-8 |
| Paraguay Division Intermedia | 2021/10/15 17:45 | Club General Diaz v 2 de Mayo | L | 3-1 |
| Paraguay Cup | 2021/10/13 21:15 | 2 de Mayo v Deportivo Santaní | L | 5-6 |
| Paraguay Division Intermedia | 2021/10/09 12:30 | 2 de Mayo v Independiente FBC | L | 0-2 |
| Paraguay Division Intermedia | 2021/10/01 21:00 | Resistencia FC v 2 de Mayo | L | 2-1 |
| Paraguay Division Intermedia | 2021/09/26 18:45 | 2 de Mayo v Fernando de la Mora | D | 0-0 |
| Paraguay Cup | 2021/09/23 19:30 | 2 de Mayo v 22 De Setiembre FBC | W | 3-0 |
| Paraguay Division Intermedia | 2021/09/19 14:00 | Deportivo Capiata v 2 de Mayo | D | 0-0 |
Away History
| Paraguay Division Profesional | 2021/12/03 22:30 | Libertad Asuncion v River Plate Asuncion | L | 5-0 |
| Paraguay Division Profesional | 2021/11/26 22:30 | River Plate Asuncion v Sportivo Luqueno | D | 0-0 |
| Paraguay Division Profesional | 2021/11/20 22:45 | Guarani Asuncion v River Plate Asuncion | L | 2-1 |
| Paraguay Division Profesional | 2021/11/05 22:00 | River Plate Asuncion v 12 de Octubre | L | 0-2 |
| Paraguay Division Profesional | 2021/10/29 22:30 | Nacional Asuncion v River Plate Asuncion | D | 1-1 |
| Paraguay Division Profesional | 2021/10/23 21:00 | River Plate Asuncion v Sol de America | L | 0-2 |
| Paraguay Division Profesional | 2021/10/18 23:30 | Cerro Porteno v River Plate Asuncion | L | 2-0 |
| Paraguay Cup | 2021/10/06 20:30 | River Plate Asuncion v Club Atlético Tembetary | L | 0-1 |