Head to Head
| Mexico U20 League | 2021/09/19 16:00 | Santos Laguna U20 v Puebla U20 | L | 4-2 |
| Mexico U20 League | 2021/05/02 16:00 | Santos Laguna U20 v Puebla U20 | W | 2-3 |
| Mexico U20 League | 2020/10/02 14:00 | Puebla U20 v Santos Laguna U20 | W | 2-1 |
| Mexico U20 League | 2020/02/07 18:00 | Puebla U20 v Santos Laguna U20 | L | 1-3 |
| Mexico U20 League | 2019/08/11 16:00 | Santos Laguna U20 v Puebla U20 | L | 5-2 |
| Mexico U20 League | 2019/01/18 18:00 | Puebla U20 v Santos Laguna U20 | D | 1-1 |
| Mexico U20 League | 2018/09/08 16:30 | Santos Laguna U20 v Puebla U20 | W | 2-3 |
| Mexico U20 League | 2018/03/16 18:00 | Puebla U20 v Santos Laguna U20 | W | 3-1 |
Home History
| Mexico U20 League | 2021/11/05 15:00 | Puebla U20 v Toluca U20 | L | 0-3 |
| Mexico U20 League | 2021/10/29 15:00 | FC Juarez U20 v Puebla U20 | D | 1-1 |
| Mexico U20 League | 2021/10/23 14:00 | Puebla U20 v Leon U20 | W | 2-1 |
| Mexico U20 League | 2021/10/19 14:00 | Puebla U20 v Mazatlan FC U20 | W | 2-1 |
| Mexico U20 League | 2021/10/15 14:00 | Necaxa U20 v Puebla U20 | D | 1-1 |
| Mexico U20 League | 2021/10/01 14:00 | Puebla U20 v Pachuca U20 | D | 1-1 |
| Mexico U20 League | 2021/09/28 14:00 | Atlas U20 v Puebla U20 | D | 3-3 |
| Mexico U20 League | 2021/09/24 14:00 | Puebla U20 v Cruz Azul U20 | D | 0-0 |
Away History
| Mexico U20 League | 2021/12/05 17:00 | Santos Laguna U20 v Cruz Azul U20 | W | 3-0 |
| Mexico U20 League | 2021/12/02 17:00 | Cruz Azul U20 v Santos Laguna U20 | L | 2-1 |
| Mexico U20 League | 2021/11/28 17:00 | Santos Laguna U20 v Atlas U20 | L | 0-1 |
| Mexico U20 League | 2021/11/25 15:00 | Atlas U20 v Santos Laguna U20 | W | 0-1 |
| Mexico U20 League | 2021/11/21 17:00 | Santos Laguna U20 v Leon U20 | W | 1-0 |
| Mexico U20 League | 2021/11/18 15:00 | Leon U20 v Santos Laguna U20 | L | 1-0 |
| Mexico U20 League | 2021/11/07 17:00 | Santos Laguna U20 v Atletico San Luis U20 | W | 2-1 |
| Mexico U20 League | 2021/11/04 15:00 | Unam Pumas U20 v Santos Laguna U20 | L | 2-1 |