[13] OTT Senators 4-1 DET Red Wings [11] 2021-11-15 15:30
Stadium: Little Caesars Arena
Home Manager: Away Manager: Jeff Blashill
Head to Head
| NHL | 2020/03/01 00:00 | DET Red Wings v OTT Senators | W | 3-4 |
| NHL | 2020/01/11 00:30 | OTT Senators v DET Red Wings | L | 2-3 |
| NHL | 2019/11/20 00:30 | OTT Senators v DET Red Wings | W | 4-3 |
| NHL | 2019/10/23 23:30 | DET Red Wings v OTT Senators | W | 2-5 |
| NHL | 2019/02/15 00:30 | OTT Senators v DET Red Wings | L | 2-3 |
| NHL | 2019/02/03 00:00 | DET Red Wings v OTT Senators | L | 2-0 |
| NHL | 2018/12/15 00:30 | OTT Senators v DET Red Wings | W | 4-2 |
| NHL | 2018/11/16 00:30 | DET Red Wings v OTT Senators | W | 1-2 |
Home History
| NHL | 2021/11/14 22:00 | CGY Flames v OTT Senators | L | 4-0 |
| NHL | 2021/11/14 00:00 | PIT Penguins v OTT Senators | W | 3-6 |
| NHL | 2021/11/12 00:00 | LA Kings v OTT Senators | L | 2-0 |
| NHL | 2021/11/10 00:00 | OTT Senators v BOS Bruins | L | 2-3 |
| NHL | 2021/11/06 18:00 | TB Lightning v OTT Senators | L | 5-3 |
| NHL | 2021/11/04 23:00 | VGS Golden Knights v OTT Senators | L | 5-1 |
| NHL | 2021/11/03 00:00 | OTT Senators v MIN Wild | L | 4-5 |
| NHL | 2021/11/02 00:00 | OTT Senators v CHI Blackhawks | L | 1-5 |
Away History
| NHL | 2021/11/14 00:00 | MTL Canadiens v DET Red Wings | W | 2-3 |
| NHL | 2021/11/12 00:30 | WAS Capitals v DET Red Wings | L | 2-0 |
| NHL | 2021/11/10 00:30 | EDM Oilers v DET Red Wings | W | 2-4 |
| NHL | 2021/11/07 23:00 | VGS Golden Knights v DET Red Wings | W | 2-5 |
| NHL | 2021/11/06 23:00 | DET Red Wings v BUF Sabres | W | 4-3 |
| NHL | 2021/11/04 23:00 | DET Red Wings v BOS Bruins | L | 1-5 |
| NHL | 2021/11/02 23:00 | DET Red Wings v MTL Canadiens | L | 0-3 |
| NHL | 2021/10/30 23:00 | DET Red Wings v TOR Maple Leafs | L | 4-5 |