Stadium: Centre Court Round: 25 Ground: Hardcourt outdoor
| Challenger Campinas | 2021/11/19 19:00 | Sebastian Baez v Nicolas Alvarez | 6-4,6-3 |
| Challenger Campinas | 2021/11/16 13:00 | Nicolas Alvarez v Pedro Cachin | 4-6,6-4,6-2 |
| Challenger Campinas | 2021/11/15 15:25 | Joao Lucas Reis da Silva v Nicolas Alvarez | 6-2,3-6,3-6 |
| Challenger Campinas | 2021/11/14 14:00 | Luis Rodrigues Batista v Nicolas Alvarez | 1-6,0-6 |
| Challenger Montevideo | 2021/11/07 16:30 | Nicolas Alvarez v Tomas Lipovsek Puches | 2-6,2-6 |
| Challenger Guayaquil | 2021/11/04 15:00 | Nicolas Alvarez v Facundo Bagnis | 2-6,6-4,1-6 |
| Challenger Guayaquil | 2021/11/02 21:45 | Nicolas Alvarez v Thiago Agustin Tirante | 4-6,7-5,6-3 |
| Challenger Guayaquil | 2021/11/01 16:00 | Nicolas Alvarez v Nicolas Barrientos | 2-6,6-4,6-4 |