[4] San Francisco FC 3-1 Herrera FC [3] 2022-02-06 13:00
Stadium: Estadio Agustín Muquita Sánchez Round: 16
Head to Head
| Panama LPF | 2021/11/13 21:00 | Herrera FC v San Francisco FC | L | 2-1 |
| Panama LPF | 2021/08/28 00:00 | San Francisco FC v Herrera FC | L | 1-3 |
| Panama LPF | 2021/05/02 22:00 | San Francisco FC v Herrera FC | D | 0-0 |
| Panama LPF | 2021/03/14 23:00 | Herrera FC v San Francisco FC | L | 1-0 |
Home History
| Panama LPF | 2022/02/06 01:00 | San Francisco FC v Veraguas CD | L | 0-1 |
| Panama LPF | 2021/11/20 21:00 | San Francisco FC v Veraguas CD | L | 0-1 |
| Panama LPF | 2021/11/13 21:00 | Herrera FC v San Francisco FC | L | 2-1 |
| Panama LPF | 2021/11/06 22:00 | San Francisco FC v CA Independiente de la Chorrera | D | 1-1 |
| Panama LPF | 2021/10/30 20:00 | CD Universitario v San Francisco FC | W | 0-1 |
| Panama LPF | 2021/10/23 01:00 | San Francisco FC v Atletico Chiriqui | W | 1-0 |
| Panama LPF | 2021/10/16 21:00 | San Francisco FC v CD Arabe Unido | W | 1-0 |
| Panama LPF | 2021/10/09 21:00 | Sporting San Miguelito v San Francisco FC | D | 1-1 |
Away History
| Panama LPF | 2022/02/05 21:00 | CD Universitario v Herrera FC | D | 2-2 |
| Panama LPF | 2021/12/12 01:00 | Tauro FC v Herrera FC | L | 3-0 |
| Panama LPF | 2021/12/04 23:00 | Herrera FC v Veraguas CD | W | 1-0 |
| Panama LPF | 2021/11/28 00:00 | Veraguas CD v Herrera FC | D | 1-1 |
| Panama LPF | 2021/11/20 21:00 | CD Universitario v Herrera FC | W | 1-2 |
| Panama LPF | 2021/11/13 21:00 | Herrera FC v San Francisco FC | W | 2-1 |
| Panama LPF | 2021/11/06 23:00 | Herrera FC v Veraguas CD | D | 1-1 |
| Panama LPF | 2021/10/30 23:00 | Atletico Chiriqui v Herrera FC | D | 0-0 |