[13] Mushuc Runa 2-0 Guayaquil City [7] 2022-01-13 08:00
Stadium: Estadio Bellavista Round: 11
Referee: Alex Fabricio Cajas Torres Home Manager: Geovanny Cumbicus Away Manager: Pool Gavilanez
Head to Head
| Ecuador LigaPro Serie A | 2021/11/21 20:30 | Mushuc Runa v Guayaquil City | W | 1-0 |
| Ecuador LigaPro Serie A | 2021/05/29 21:30 | Guayaquil City v Mushuc Runa | D | 0-0 |
| Ecuador LigaPro Serie A | 2020/11/14 18:00 | Guayaquil City v Mushuc Runa | L | 3-2 |
| Ecuador LigaPro Serie A | 2020/09/26 19:45 | Mushuc Runa v Guayaquil City | W | 2-1 |
| Ecuador LigaPro Serie A | 2019/08/25 19:45 | Guayaquil City v Mushuc Runa | L | 4-2 |
| Ecuador LigaPro Serie A | 2019/04/06 20:00 | Mushuc Runa v Guayaquil City | W | 3-2 |
| Ecuador LigaPro Serie A | 2016/10/30 17:00 | Mushuc Runa v Guayaquil City | L | 0-2 |
| Ecuador LigaPro Serie A | 2016/09/10 21:00 | Guayaquil City v Mushuc Runa | D | 0-0 |
Home History
| Ecuador LigaPro Serie A | 2021/11/28 01:00 | Delfin SC v Mushuc Runa | L | 3-0 |
| Ecuador LigaPro Serie A | 2021/11/21 20:30 | Mushuc Runa v Guayaquil City | W | 1-0 |
| Ecuador LigaPro Serie A | 2021/11/06 00:00 | Emelec v Mushuc Runa | L | 2-0 |
| Ecuador LigaPro Serie A | 2021/10/31 19:00 | Mushuc Runa v Deportivo Cuenca | W | 1-0 |
| Ecuador LigaPro Serie A | 2021/10/23 20:00 | Universidad Catolica del Ecuador v Mushuc Runa | W | 0-1 |
| Ecuador LigaPro Serie A | 2021/10/17 19:00 | Mushuc Runa v Tecnico Universitario | L | 0-1 |
| Ecuador LigaPro Serie A | 2021/10/03 21:30 | Barcelona Guayaquil v Mushuc Runa | L | 4-0 |
| Ecuador LigaPro Serie A | 2021/09/25 20:00 | Mushuc Runa v Orense | D | 0-0 |
Away History
| Ecuador LigaPro Serie A | 2021/11/28 01:00 | Guayaquil City v SD Aucas | W | 1-0 |
| Ecuador LigaPro Serie A | 2021/11/21 20:30 | Mushuc Runa v Guayaquil City | L | 1-0 |
| Ecuador LigaPro Serie A | 2021/11/08 00:00 | Guayaquil City v Independiente del Valle | L | 0-2 |
| Ecuador LigaPro Serie A | 2021/10/31 01:00 | Guayaquil City v Emelec | L | 0-1 |
| Ecuador LigaPro Serie A | 2021/10/24 21:00 | Manta FC v Guayaquil City | D | 1-1 |
| Ecuador LigaPro Serie A | 2021/10/16 20:00 | Guayaquil City v Olmedo | W | 4-2 |
| Ecuador LigaPro Serie A | 2021/10/03 01:00 | LDU Quito v Guayaquil City | L | 3-1 |
| Ecuador LigaPro Serie A | 2021/09/25 22:30 | Guayaquil City v Club 9 de Octubre | L | 0-1 |