Stadium: Gainbridge Fieldhouse Round: 122
Home Manager: Todd Golden Away Manager: Matt McMahon
| NCAAB | 2021/11/27 04:30 | San Francisco v UAB | W | 63-61 |
| NCAAB | 2021/11/26 02:30 | San Francisco v Towson | W | 71-61 |
| NCAAB | 2021/11/23 02:00 | Morgan State v San Francisco | W | 67-83 |
| NCAAB | 2021/11/19 03:30 | Nevada v San Francisco | W | 70-73 |
| NCAAB | 2021/11/16 02:00 | Samford v San Francisco | W | 55-77 |
| NCAAB | 2021/11/14 01:30 | Davidson v San Francisco | W | 60-65 |
| NCAAB | 2021/11/12 03:30 | Prairie View v San Francisco | W | 76-92 |
| NCAAB | 2021/11/10 03:30 | LIU Brooklyn v San Francisco | W | 64-98 |
| NCAAB | 2021/11/24 19:30 | James Madison v Murray State | W | 62-74 |
| NCAAB | 2021/11/23 19:30 | Murray State v Long Beach State | W | 80-43 |
| NCAAB | 2021/11/22 22:30 | East Tenn St v Murray State | L | 66-58 |
| NCAAB | 2021/11/17 01:00 | Murray State v Illinois St | W | 77-65 |
| NCAAB | 2021/11/14 01:00 | Bellarmine v Murray State | W | 59-78 |
| NCAAB | 2021/11/10 01:00 | Murray State v Cumberland Phoenix | W | 109-77 |
| NCAAB | 2021/03/05 01:00 | Murray State v Jacksonville St | L | 65-68 |
| NCAAB | 2021/02/28 02:00 | Murray State v Tennessee Tech | L | 61-71 |