Stadium: Carver-Hawkeye Arena Round: 122
Home Manager: Kristen Gillespie Away Manager: Lisa Bluder
| WNCAAB | 2021/03/22 21:00 | Tennessee Martin (W) v Illinois State (W) | L | 64-59 |
| WNCAAB | 2021/03/20 19:00 | Samford (W) v Illinois State (W) | W | 62-68 |
| WNCAAB | 2021/03/20 01:00 | Illinois State (W) v Tulane (W) | L | 67-75 |
| WNCAAB | 2021/03/13 02:00 | Loyola Chicago (W) v Illinois State (W) | L | 61-60 |
| WNCAAB | 2021/03/06 21:00 | Illinois State (W) v Loyola Chicago (W) | W | 60-45 |
| WNCAAB | 2021/03/05 21:00 | Illinois State (W) v Loyola Chicago (W) | W | 64-61 |
| WNCAAB | 2021/02/26 00:00 | Bradley Women v Illinois State (W) | W | 59-79 |
| WNCAAB | 2021/02/20 22:00 | Illinois State (W) v Drake (W) | W | 81-71 |
| WNCAAB | 2021/03/27 17:00 | Iowa (W) v Connecticut (W) | L | 72-92 |
| WNCAAB | 2021/03/23 19:30 | Iowa (W) v Kentucky (W) | W | 86-72 |
| WNCAAB | 2021/03/21 16:00 | Central Michigan (W) v Iowa (W) | W | 72-87 |
| WNCAAB | 2021/03/13 19:00 | Iowa (W) v Maryland (W) | L | 84-104 |
| WNCAAB | 2021/03/12 21:30 | Michigan State (W) v Iowa (W) | W | 72-87 |
| WNCAAB | 2021/03/12 02:00 | Iowa (W) v Rutgers (W) | W | 73-62 |
| WNCAAB | 2021/03/11 02:00 | Purdue (W) v Iowa (W) | W | 72-83 |
| WNCAAB | 2021/03/07 01:00 | Nebraska (W) v Iowa (W) | W | 75-83 |