| Panama Liga Prom | 2021/09/25 20:00 | Union Cocle v SD Panama Oeste | L | 0-2 |
| Panama Liga Prom | 2021/03/30 23:00 | SD Panama Oeste v Union Cocle | W | 1-2 |
| Panama Liga Prom | 2021/11/18 23:00 | Atletico Chiriqui B v Union Cocle | W | 1-4 |
| Panama Liga Prom | 2021/11/12 20:00 | Union Cocle v CD Universitario Reserves | L | 0-3 |
| Panama Liga Prom | 2021/11/06 00:00 | Mario Mendez FC v Union Cocle | L | 3-0 |
| Panama Liga Prom | 2021/10/31 20:00 | Union Cocle v Veraguas United Reserves | L | 0-4 |
| Panama Liga Prom | 2021/10/20 23:01 | Herrera FC Reserves v Union Cocle | L | 3-0 |
| Panama Liga Prom | 2021/10/17 00:00 | San Francisco Reserves v Union Cocle | L | 3-0 |
| Panama Liga Prom | 2021/10/02 22:00 | CA Independiente de la Chorrera Reserves v Union Cocle | L | 4-0 |
| Panama Liga Prom | 2021/09/25 20:00 | Union Cocle v SD Panama Oeste | L | 0-2 |
| Panama Liga Prom | 2021/12/17 00:00 | Alianza FC Reserves v SD Panama Oeste | L | 4-1 |
| Panama Liga Prom | 2021/12/11 00:00 | Plaza Amador Reserves v SD Panama Oeste | D | 1-1 |
| Panama Liga Prom | 2021/12/06 00:00 | SD Atletico Nacional v SD Panama Oeste | W | 1-2 |
| Panama Liga Prom | 2021/11/30 00:00 | Mario Mendez FC v SD Panama Oeste | L | 1-0 |
| Panama Liga Prom | 2021/11/26 00:00 | SD Panama Oeste v Mario Mendez FC | W | 2-0 |
| Panama Liga Prom | 2021/11/19 21:00 | San Francisco Reserves v SD Panama Oeste | W | 0-1 |
| Panama Liga Prom | 2021/11/12 22:00 | SD Panama Oeste v Aguilas de la U | W | 1-0 |
| Panama Liga Prom | 2021/11/06 01:00 | CA Independiente de la Chorrera Reserves v SD Panama Oeste | D | 0-0 |