[24] Karen Khachanov 7-6,3-6,3-6 Diego Schwartzman [16] 2022-02-22 12:55
Stadium: Court Des Princes Round: 24 Ground: Clay
Head to Head
| Olympics 2020 - Men | 2021/07/28 03:15 | Diego Schwartzman v Karen Khachanov | 1-6,6-2,1-6 |
| ATP Vienna | 2019/10/25 15:30 | Diego Schwartzman v Karen Khachanov | 7-6,6-2 |
| Boodles Challenge | 2019/06/28 14:50 | Karen Khachanov v Diego Schwartzman | 6-7,6-3,4-10 |
| ATP Cincinnati | 2017/08/15 15:00 | Diego Schwartzman v Karen Khachanov | 1-6,6-1,3-6 |
| ATP Miami | 2017/03/23 17:20 | Karen Khachanov v Diego Schwartzman | 4-6,6-3,6-7 |
Home History
| ATP Dubai | 2022/02/22 10:00 | Karen Khachanov v Alex De Minaur | 6-3,6-7,7-5 |
| ATP Doha | 2022/02/18 16:30 | Karen Khachanov v Roberto Bautista-Agut | 6-2,3-6,5-7 |
| ATP Doha | 2022/02/17 17:15 | Karen Khachanov v Marin Cilic | 3-6,6-3,6-4 |
| ATP Doha | 2022/02/16 16:25 | Karen Khachanov v Emil Ruusuvuori | 7-6,6-3 |
| ATP Doha | 2022/02/14 16:15 | Karen Khachanov v Mackenzie McDonald | 7-6,6-3 |
| ATP Rotterdam | 2022/02/09 20:30 | Cameron Norrie v Karen Khachanov | 6-4,7-6 |
| ATP Rotterdam | 2022/02/08 12:00 | Karen Khachanov v Alexei Popyrin | 6-7,6-1,7-6 |
| Australian Open | 2022/01/21 10:10 | Karen Khachanov v Rafael Nadal | 3-6,2-6,6-3,1-6 |
Away History
| ATP Rio De Janeiro | 2022/02/20 20:30 | Carlos Alcaraz Garfia v Diego Schwartzman | 6-4,6-2 |
| ATP Rio De Janeiro | 2022/02/19 23:10 | Diego Schwartzman v Francisco Cerundolo | 7-6,6-3 |
| ATP Rio De Janeiro | 2022/02/19 15:00 | Pablo Andujar v Diego Schwartzman | 6-7,6-4,4-6 |
| ATP Rio De Janeiro | 2022/02/17 02:15 | Pedro Martinez v Diego Schwartzman | 1-6,1-6 |
| ATP Buenos Aires | 2022/02/13 19:00 | Casper Ruud v Diego Schwartzman | 5-7,6-2,6-3 |
| ATP Buenos Aires | 2022/02/12 21:00 | Lorenzo Sonego v Diego Schwartzman | 5-7,6-3,2-6 |
| ATP Buenos Aires | 2022/02/11 23:50 | Francisco Cerundolo v Diego Schwartzman | 6-3,2-6,5-7 |
| ATP Buenos Aires | 2022/02/10 23:50 | Jaume Munar v Diego Schwartzman | 6-7,6-7 |