[5] Troy 10-6 South Alabama [4] 2022-07-16 07:30
Stadium: Hancock Whitney Stadium Round: 1
Home Manager: Kane Wommack Away Manager: Jon Sumrall
Head to Head
| NCAAF | 2021/11/06 19:30 | South Alabama v Troy | W | 24-31 |
| NCAAF | 2020/12/05 19:00 | Troy v South Alabama | W | 29-0 |
| NCAAF | 2019/10/17 00:00 | South Alabama v Troy | W | 13-37 |
| NCAAF | 2018/10/24 00:00 | Troy v South Alabama | W | 38-17 |
| NCAAF | 2017/10/12 00:00 | South Alabama v Troy | L | 19-8 |
| NCAAF | 2016/10/20 23:30 | Troy v South Alabama | W | 28-21 |
| NCAAF | 2015/10/03 23:00 | Troy v South Alabama | L | 18-24 |
| NCAAF | 2014/10/24 23:30 | South Alabama v Troy | L | 27-13 |
Home History
| NCAAF | 2021/11/27 19:00 | Troy v Georgia State | L | 10-37 |
| NCAAF | 2021/11/20 20:30 | Appalachian St v Troy | L | 45-7 |
| NCAAF | 2021/11/13 20:30 | Lafayette v Troy | L | 35-21 |
| NCAAF | 2021/11/06 19:30 | South Alabama v Troy | W | 24-31 |
| NCAAF | 2021/10/28 23:30 | Troy v Coastal Carolina | L | 28-35 |
| NCAAF | 2021/10/16 19:00 | Troy v Texas State | W | 31-28 |
| NCAAF | 2021/10/09 23:00 | Georgia Southern v Troy | W | 24-27 |
| NCAAF | 2021/10/02 19:30 | Troy v South Carolina | L | 14-23 |
Away History
| NCAAF | 2021/11/26 20:30 | Coastal Carolina v South Alabama | L | 27-21 |
| NCAAF | 2021/11/21 00:30 | South Alabama v Tennessee | L | 14-60 |
| NCAAF | 2021/11/13 19:30 | South Alabama v Appalachian St | L | 7-31 |
| NCAAF | 2021/11/06 19:30 | South Alabama v Troy | L | 24-31 |
| NCAAF | 2021/10/30 21:00 | Arkansas State v South Alabama | W | 13-31 |
| NCAAF | 2021/10/23 23:00 | South Alabama v UL Monroe | L | 31-41 |
| NCAAF | 2021/10/14 23:30 | Georgia Southern v South Alabama | W | 14-41 |
| NCAAF | 2021/10/09 23:00 | South Alabama v Texas State | L | 31-33 |