[65] Nick Kyrgios 5-7,6-2,6-4 Stefanos Tsitsipas [6] 2022-04-22 19:30
Stadium: OWL Arena Round: 26 Ground: Grass
Head to Head
| Laver Cup | 2021/09/25 17:00 | Stefanos Tsitsipas v Nick Kyrgios | 6-3,6-4 |
| ATP Cup | 2020/01/07 10:20 | Stefanos Tsitsipas v Nick Kyrgios | 6-7,7-6,6-7 |
| ATP Washington | 2019/08/03 23:00 | Stefanos Tsitsipas v Nick Kyrgios | 4-6,6-3,6-7 |
Home History
| ATP Houston | 2022/04/09 18:00 | Nick Kyrgios v Reilly Opelka | 3-6,5-7 |
| ATP Houston | 2022/04/06 20:35 | Nick Kyrgios v Tommy Paul | 6-4,6-2 |
| ATP Houston | 2022/04/05 21:10 | Mackenzie McDonald v Nick Kyrgios | 6-4,3-6,4-6 |
| ATP Miami | 2022/03/29 16:50 | Nick Kyrgios v Jannik Sinner | 6-7,3-6 |
| ATP Miami | 2022/03/27 17:35 | Nick Kyrgios v Fabio Fognini | 6-2,6-4 |
| ATP Miami | 2022/03/25 20:10 | Andrey Rublev v Nick Kyrgios | 3-6,0-6 |
| ATP Miami | 2022/03/24 00:55 | Nick Kyrgios v Adrian Mannarino | 7-6,6-3 |
| ATP Indian Wells | 2022/03/17 22:00 | Rafael Nadal v Nick Kyrgios | 7-6,5-7,6-4 |
Away History
| ATP Barcelona | 2022/04/22 18:15 | Stefanos Tsitsipas v Carlos Alcaraz Garfia | 4-6,7-5,2-6 |
| ATP Barcelona | 2022/04/22 12:55 | Stefanos Tsitsipas v Grigor Dimitrov | 6-1,6-4 |
| ATP Barcelona | 2022/04/20 16:35 | Stefanos Tsitsipas v Ilya Ivashka | 6-1,4-6,6-2 |
| ATP Monte Carlo | 2022/04/17 12:30 | Alejandro Davidovich Fokina v Stefanos Tsitsipas | 3-6,6-7 |
| ATP Monte Carlo | 2022/04/16 14:40 | Stefanos Tsitsipas v Alexander Zverev | 6-4,6-2 |
| ATP Monte Carlo | 2022/04/15 18:05 | Diego Schwartzman v Stefanos Tsitsipas | 2-6,7-6,4-6 |
| ATP Monte Carlo | 2022/04/14 10:50 | Laslo Djere v Stefanos Tsitsipas | 5-7,6-7 |
| ATP Monte Carlo | 2022/04/12 16:35 | Fabio Fognini v Stefanos Tsitsipas | 3-6,0-6 |