[8] Brentford 3-0 Southampton [20] 2022-09-15 23:00
Stadium: Brentford Community Stadium Round: 22
Referee: Darren Bond Home Manager: Thomas Frank Away Manager: Nathan Jones
Head to Head
| England Premier League | 2022/05/07 14:00 | Brentford v Southampton | W | 3-0 |
| England Premier League | 2022/01/11 19:45 | Southampton v Brentford | L | 4-1 |
| England EFL Cup | 2020/09/16 18:45 | Southampton v Brentford | W | 0-2 |
| Elite Club Friendlies | 2017/07/22 14:00 | Brentford v Southampton | D | 2-2 |
Home History
| England Premier League | 2022/09/03 14:00 | Brentford v Leeds | W | 5-2 |
| England Premier League | 2022/08/30 18:30 | Crystal Palace v Brentford | D | 1-1 |
| England Premier League | 2022/08/27 14:00 | Brentford v Everton | D | 1-1 |
| England EFL Cup | 2022/08/23 18:45 | Colchester v Brentford | W | 0-2 |
| England Premier League | 2022/08/20 14:00 | Fulham v Brentford | L | 3-2 |
| England Premier League | 2022/08/13 16:30 | Brentford v Man Utd | W | 4-0 |
| England Premier League | 2022/08/07 13:00 | Leicester v Brentford | D | 2-2 |
| Elite Club Friendlies | 2022/07/30 14:00 | Brentford v Real Betis | W | 1-0 |
Away History
| England Premier League | 2022/09/03 14:00 | Wolverhampton v Southampton | L | 1-0 |
| England Premier League | 2022/08/30 18:45 | Southampton v Chelsea | W | 2-1 |
| England Premier League | 2022/08/27 11:30 | Southampton v Man Utd | L | 0-1 |
| England EFL Cup | 2022/08/23 18:45 | Cambridge Utd v Southampton | W | 0-3 |
| England Premier League | 2022/08/20 14:00 | Leicester v Southampton | W | 1-2 |
| England Premier League | 2022/08/13 14:00 | Southampton v Leeds | D | 2-2 |
| England Premier League | 2022/08/06 14:00 | Tottenham v Southampton | L | 4-1 |
| Elite Club Friendlies | 2022/07/30 14:00 | Southampton v Villarreal | L | 1-2 |