South Dakota 3-28 South Dakota State 2022-05-15 03:00
Stadium: Dana J. Dykhouse Stadium Round: 1
Home Manager: Bob Nielson Away Manager: John Stiegelmeier
Head to Head
| NCAAF | 2021/11/13 19:00 | South Dakota State v South Dakota | W | 20-23 |
| NCAAF | 2019/11/23 20:00 | South Dakota State v South Dakota | W | 21-24 |
| NCAAF FCS | 2018/11/17 20:00 | South Dakota v South Dakota State | L | 27-49 |
| NCAAF | 2017/11/18 20:00 | South Dakota v South Dakota State | L | 28-31 |
Home History
| NCAAF | 2021/11/27 23:00 | SO Illinois v South Dakota | L | 22-10 |
| NCAAF | 2021/11/20 20:30 | South Dakota v North Dakota State | L | 24-52 |
| NCAAF | 2021/11/13 19:00 | South Dakota State v South Dakota | W | 20-23 |
| NCAAF | 2021/11/06 17:00 | South Dakota v Western Illinois | W | 42-21 |
| NCAAF | 2021/10/23 18:00 | Illinois State v South Dakota | L | 20-14 |
| NCAAF | 2021/10/16 21:00 | South Dakota v Northern Iowa | W | 34-21 |
| NCAAF | 2021/10/09 19:00 | North Dakota v South Dakota | W | 13-20 |
| NCAAF | 2021/10/02 19:00 | Indiana State v South Dakota | W | 10-38 |
Away History
| NCAAF | 2021/12/18 19:00 | South Dakota State v Montana State | L | 17-31 |
| NCAAF | 2021/12/11 19:00 | South Dakota State v Villanova | W | 35-21 |
| NCAAF | 2021/12/05 02:00 | South Dakota State v CS Sacramento | W | 24-19 |
| NCAAF | 2021/11/27 20:00 | UC Davis v South Dakota State | W | 24-56 |
| NCAAF | 2021/11/20 20:00 | North Dakota v South Dakota State | W | 21-24 |
| NCAAF | 2021/11/13 19:00 | South Dakota State v South Dakota | L | 20-23 |
| NCAAF | 2021/11/06 19:00 | North Dakota State v South Dakota State | W | 19-27 |
| NCAAF | 2021/10/30 18:00 | South Dakota State v Youngstown State | W | 47-16 |