[2] Syracuse 9-19 Pittsburgh [12] 2022-09-10 23:30
Stadium: Acrisure Stadium Round: 1
Home Manager: Dino Babers Away Manager: Pat Narduzzi
Head to Head
| NCAAF | 2021/11/28 00:30 | Pittsburgh v Syracuse | L | 31-14 |
| NCAAF | 2020/09/19 16:00 | Syracuse v Pittsburgh | L | 10-21 |
| NCAAF | 2019/10/18 23:00 | Pittsburgh v Syracuse | L | 27-20 |
| NCAAF | 2018/10/06 16:20 | Syracuse v Pittsburgh | L | 37-44 |
| NCAAF | 2017/10/07 16:30 | Pittsburgh v Syracuse | W | 24-27 |
| NCAAF | 2016/11/26 17:30 | Syracuse v Pittsburgh | L | 61-76 |
| NCAAF | 2015/10/24 16:00 | Syracuse v Pittsburgh | L | 20-23 |
| NCAAF | 2014/11/22 20:30 | Pittsburgh v Syracuse | L | 30-7 |
Home History
| NCAAF | 2022/09/10 23:00 | Syracuse v Connecticut | W | 48-14 |
| NCAAF | 2022/09/04 00:00 | Louisville v Syracuse | W | 7-31 |
| NCAAF | 2021/11/28 00:30 | Pittsburgh v Syracuse | L | 31-14 |
| NCAAF | 2021/11/20 21:00 | Syracuse v NC State | L | 17-41 |
| NCAAF | 2021/11/13 17:00 | Syracuse v Louisville | L | 3-41 |
| NCAAF | 2021/10/30 19:30 | Boston College v Syracuse | W | 6-21 |
| NCAAF | 2021/10/23 16:30 | Syracuse v Virginia Tech | W | 41-36 |
| NCAAF | 2021/10/15 23:00 | Clemson v Syracuse | L | 17-14 |
Away History
| NCAAF | 2022/09/10 19:30 | Tennessee v Pittsburgh | L | 34-27 |
| NCAAF | 2022/09/01 23:00 | West Virginia v Pittsburgh | W | 31-38 |
| NCAAF Bowl Games | 2021/12/31 00:00 | Pittsburgh v Michigan State | L | 21-31 |
| NCAAF | 2021/12/05 01:00 | Wake Forest v Pittsburgh | W | 21-45 |
| NCAAF | 2021/11/28 00:30 | Pittsburgh v Syracuse | W | 31-14 |
| NCAAF | 2021/11/20 20:30 | Virginia v Pittsburgh | W | 38-48 |
| NCAAF | 2021/11/12 00:30 | North Carolina v Pittsburgh | W | 23-30 |
| NCAAF | 2021/11/06 16:00 | Pittsburgh v Duke | W | 54-29 |