| Paraguay Women League | 2022/05/03 19:00 | Guairena FC Women v Club Guarani (W) | W | 1-3 |
| Paraguay Women League | 2022/05/03 19:00 | Guairena FC Women v Club Guarani (W) | W | 1-3 |
| Paraguay Women League | 2022/04/30 19:00 | Club Guarani (W) v River Plate Asuncion Women | W | 3-0 |
| Paraguay Women League | 2022/04/23 19:00 | Nacional-Humaita (W) v Club Guarani (W) | L | 1-0 |
| Paraguay Women League | 2022/03/24 20:00 | Club Guarani (W) v Sportivo Ameliano Women | W | 8-0 |
| Paraguay Women League | 2022/03/19 12:00 | Tacuary Women v Club Guarani (W) | W | 1-3 |
| Paraguay Women League | 2022/03/13 12:00 | Club Guarani (W) v Sol de America Women | L | 0-2 |
| Paraguay Women League | 2022/03/06 12:00 | General Caballero JLM (W) v Club Guarani (W) | D | 2-2 |
| Paraguay Women League | 2022/02/25 13:00 | Club Guarani (W) v Cerro Porteno (W) | L | 2-5 |
| Paraguay Women League | 2022/05/03 19:00 | Guairena FC Women v Club Guarani (W) | L | 1-3 |
| Paraguay Women League | 2022/04/30 19:00 | Sportivo Ameliano Women v Guairena FC Women | W | 0-3 |
| Paraguay Women League | 2022/03/06 12:00 | Resistencia FC Women v Guairena FC Women | D | 1-1 |
| Paraguay Women League | 2021/06/05 19:00 | 12 De Octubre Itaugua Women v Guairena FC Women | L | 5-1 |