Stadium: Rogers Stadium Round: 1
| NCAAF | 2021/11/06 18:00 | Virginia Union Panthers v Virginia State Trojans | L | 20-13 |
| NCAAF | 2021/10/30 18:00 | Virginia State Trojans v Chowan Hawks | L | 30-38 |
| NCAAF | 2021/10/23 18:00 | Virginia State Trojans v Lincoln University | W | 23-3 |
| NCAAF | 2021/10/16 17:00 | Bowie State Bulldogs v Virginia State Trojans | L | 51-44 |
| NCAAF | 2021/10/09 22:00 | Virginia State Trojans v Elizabeth City State Vikings | W | 35-7 |
| NCAAF | 2021/10/02 22:00 | Virginia State Trojans v St Augustines Falcons | W | 33-9 |
| NCAAF | 2021/09/25 23:00 | Fayetteville State Broncos v Virginia State Trojans | L | 28-14 |
| NCAAF | 2021/09/11 17:00 | Ohio Dominican Panthers v Virginia State Trojans | L | 10-7 |
| NCAAF | 2021/10/30 18:00 | Barton Bulldogs v Bluefield State | L | 62-7 |
| NCAAF | 2021/10/16 20:00 | Erskine Flying Fleet v Bluefield State | L | 24-19 |
| NCAAF | 2021/10/09 17:08 | Bluefield State v Fort Lauderdale Soaring Eagles | W | 23-9 |
| NCAAF | 2021/09/18 22:00 | Johnson C Smith GB v Bluefield State | W | 12-20 |
| NCAAF | 2021/09/11 17:30 | Elizabeth City State Vikings v Bluefield State | W | 27-35 |
| NCAAF | 2021/09/04 16:00 | Bluefield State v Lawrence Tech Blue Devils | L | 14-21 |