Stadium: Durham County Memorial Stadium Round: 1
| NCAAF | 2021/11/06 17:00 | St Augustines Falcons v Shaw Bears | L | 21-17 |
| NCAAF | 2021/10/30 17:00 | Shaw Bears v Winston-Salem State | W | 38-14 |
| NCAAF | 2021/10/23 17:00 | Shaw Bears v Johnson C Smith GB | W | 20-14 |
| NCAAF | 2021/10/16 17:00 | Livingstone C. BB v Shaw Bears | W | 9-20 |
| NCAAF | 2021/10/09 17:00 | Shaw Bears v Fayetteville State Broncos | L | 12-15 |
| NCAAF | 2021/10/02 17:00 | Virginia Union Panthers v Shaw Bears | W | 7-27 |
| NCAAF | 2021/09/25 17:00 | Lincoln University v Shaw Bears | W | 6-41 |
| NCAAF | 2021/09/18 17:00 | Shaw Bears v Central State | W | 52-0 |
| NCAAF | 2021/11/06 17:00 | Bowie State Bulldogs v Elizabeth City State Vikings | L | 79-6 |
| NCAAF | 2021/10/30 17:00 | Elizabeth City State Vikings v Virginia Union Panthers | L | 14-44 |
| NCAAF | 2021/10/23 17:30 | Elizabeth City State Vikings v Chowan Hawks | W | 32-28 |
| NCAAF | 2021/10/16 17:00 | Lincoln University v Elizabeth City State Vikings | L | 17-14 |
| NCAAF | 2021/10/09 22:00 | Virginia State Trojans v Elizabeth City State Vikings | L | 35-7 |
| NCAAF | 2021/10/02 18:30 | Elizabeth City State Vikings v Livingstone C. BB | W | 19-13 |
| NCAAF | 2021/09/25 17:30 | Winston-Salem State v Elizabeth City State Vikings | W | 14-19 |
| NCAAF | 2021/09/18 22:00 | Norfolk State v Elizabeth City State Vikings | L | 63-26 |