Stadium: Mattke Field Round: 1
| NCAAF | 2019/10/05 20:00 | Minot State Beavers v Southwest Minnesota State Mustangs | W | 17-21 |
| NCAAF | 2021/11/13 19:00 | Augustana Vikings v Southwest Minnesota State Mustangs | L | 55-0 |
| NCAAF | 2021/11/06 18:00 | Southwest Minnesota State Mustangs v Minnesota State Mankato Mavericks | L | 0-52 |
| NCAAF | 2021/10/30 18:00 | Bemidji State Beavers v Southwest Minnesota State Mustangs | L | 48-14 |
| NCAAF | 2021/10/23 22:00 | Southwest Minnesota State Mustangs v Wayne State Wildcats | L | 16-38 |
| NCAAF | 2021/10/16 18:00 | Winona State Warriors v Southwest Minnesota State Mustangs | L | 26-14 |
| NCAAF | 2021/10/09 22:00 | Southwest Minnesota State Mustangs v Sioux Falls Cougars | L | 7-35 |
| NCAAF | 2021/10/02 20:00 | Upper Iowa v Southwest Minnesota State Mustangs | W | 14-20 |
| NCAAF | 2021/09/25 17:00 | Concordia University Golden Bears v Southwest Minnesota State Mustangs | W | 24-34 |
| NCAAF | 2021/11/13 17:00 | Minot State Beavers v Concordia University Golden Bears | W | 28-20 |
| NCAAF | 2021/11/06 19:00 | University of Mary Marauders v Minot State Beavers | L | 49-31 |
| NCAAF | 2021/10/30 18:00 | Minot State Beavers v Minnesota Duluth Bulldogs | L | 21-34 |
| NCAAF | 2021/10/23 16:00 | Minot State Beavers v Upper Iowa | W | 17-14 |
| NCAAF | 2021/10/16 23:00 | Northern State Wolves v Minot State Beavers | L | 36-35 |
| NCAAF | 2021/10/09 19:00 | Minot State Beavers v Minnesota State University Moorhead Dragons | L | 17-29 |
| NCAAF | 2021/10/02 19:00 | Bemidji State Beavers v Minot State Beavers | L | 49-35 |
| NCAAF | 2021/09/25 23:00 | Minot State Beavers v Minnesota State Mankato Mavericks | L | 10-68 |