Stadium: McConnell Family Stadium Round: 1
| NCAAF | 2021/10/16 20:00 | Seton Hill Griffins v Gannon University Golden Knights | W | 10-14 |
| NCAAF | 2019/10/12 20:00 | Seton Hill Griffins v Gannon University Golden Knights | L | 25-21 |
| NCAAF | 2018/10/06 16:00 | Gannon University Golden Knights v Seton Hill Griffins | W | 48-28 |
| NCAAF | 2022/09/10 16:00 | Millersville University of Pennsylvania Marauders v Gannon University Golden Knights | W | 10-16 |
| NCAAF | 2022/09/01 23:00 | Gannon University Golden Knights v University of Charleston Golden Eagles | W | 47-13 |
| NCAAF | 2021/11/13 18:05 | East Stroudsburg Warriors v Gannon University Golden Knights | W | 10-13 |
| NCAAF | 2021/11/06 16:00 | Mercyhurst v Gannon University Golden Knights | L | 24-13 |
| NCAAF | 2021/10/30 16:00 | Gannon University Golden Knights v Slippery Rock | L | 21-63 |
| NCAAF | 2021/10/23 16:00 | Gannon University Golden Knights v Edinboro | W | 21-18 |
| NCAAF | 2021/10/16 20:00 | Seton Hill Griffins v Gannon University Golden Knights | W | 10-14 |
| NCAAF | 2021/10/09 16:00 | Gannon University Golden Knights v California Vulcans | L | 17-38 |
| NCAAF | 2022/09/10 17:00 | Shippensburg Raiders v Seton Hill Griffins | L | 36-17 |
| NCAAF | 2022/09/01 23:00 | Wheeling v Seton Hill Griffins | L | 25-11 |
| NCAAF | 2021/11/13 18:00 | Lock Haven v Seton Hill Griffins | W | 7-59 |
| NCAAF | 2021/11/06 16:00 | Seton Hill Griffins v Iup Crimson Hawks | L | 3-38 |
| NCAAF | 2021/10/30 20:00 | California Vulcans v Seton Hill Griffins | L | 42-14 |
| NCAAF | 2021/10/23 16:00 | Clarion Golden Eagles v Seton Hill Griffins | W | 0-49 |
| NCAAF | 2021/10/16 20:00 | Seton Hill Griffins v Gannon University Golden Knights | L | 10-14 |
| NCAAF | 2021/10/09 16:00 | Mercyhurst v Seton Hill Griffins | W | 17-19 |