Stadium: Leckonby Stadium Round: 1
| NCAAF | 2021/10/09 17:00 | Union Dutchmen v St Lawrence Saints | L | 37-7 |
| NCAAF | 2019/10/19 17:00 | Union Dutchmen v St Lawrence Saints | L | 38-17 |
| NCAAF | 2018/10/20 17:00 | St Lawrence Saints v Union Dutchmen | L | 7-29 |
| NCAAF | 2021/11/13 17:00 | Buffalo State Bengals v St Lawrence Saints | W | 6-41 |
| NCAAF | 2021/11/06 17:00 | St Lawrence Saints v Rpi Engineers | L | 20-22 |
| NCAAF | 2021/10/30 17:00 | St Lawrence Saints v Rochester Yellowjackets | W | 34-10 |
| NCAAF | 2021/10/23 17:00 | Hobart Statesmen v St Lawrence Saints | L | 17-13 |
| NCAAF | 2021/10/16 17:00 | St Lawrence Saints v Ithaca Bombers | L | 0-17 |
| NCAAF | 2021/10/09 17:00 | Union Dutchmen v St Lawrence Saints | L | 37-7 |
| NCAAF | 2021/09/25 20:00 | St Lawrence Saints v Castleton Spartans | W | 55-3 |
| NCAAF | 2021/09/17 23:00 | Morrisville State Mustangs v St Lawrence Saints | W | 14-27 |
| NCAAF | 2021/11/13 17:00 | Union Dutchmen v Rpi Engineers | L | 17-19 |
| NCAAF | 2021/11/06 17:00 | Ithaca Bombers v Union Dutchmen | L | 26-7 |
| NCAAF | 2021/10/30 17:00 | Union Dutchmen v Hobart Statesmen | W | 27-20 |
| NCAAF | 2021/10/23 16:00 | Rochester Yellowjackets v Union Dutchmen | W | 9-35 |
| NCAAF | 2021/10/09 17:00 | Union Dutchmen v St Lawrence Saints | W | 37-7 |
| NCAAF | 2021/10/02 16:00 | Buffalo State Bengals v Union Dutchmen | W | 17-30 |
| NCAAF | 2021/09/25 17:00 | Utica Pioneers v Union Dutchmen | W | 9-30 |
| NCAAF | 2021/09/18 20:30 | Union Dutchmen v Springfield Pride | W | 30-23 |