Stadium: University of Charleston Stadium Round: 1
| NCAAF | 2021/10/23 18:00 | Unc Pembroke Braves v University of Charleston Golden Eagles | L | 21-14 |
| NCAAF | 2021/11/13 17:00 | West Virginia State Yellow Jackets v University of Charleston Golden Eagles | W | 13-38 |
| NCAAF | 2021/11/06 16:00 | University of Charleston Golden Eagles v Wheeling | W | 38-20 |
| NCAAF | 2021/10/28 23:00 | University of Charleston Golden Eagles v W. Virginia Bobcats | W | 45-6 |
| NCAAF | 2021/10/23 18:00 | Unc Pembroke Braves v University of Charleston Golden Eagles | L | 21-14 |
| NCAAF | 2021/10/16 16:00 | University of Charleston Golden Eagles v Concord University Mountain Lions | W | 48-3 |
| NCAAF | 2021/10/09 17:00 | Glenville State Pioneers v University of Charleston Golden Eagles | W | 9-20 |
| NCAAF | 2021/10/02 16:00 | University of Charleston Golden Eagles v Notre Dame Falcons | W | 38-28 |
| NCAAF | 2021/09/25 17:00 | Alderson Broaddus Battlers v University of Charleston Golden Eagles | W | 7-69 |
| NCAAF | 2021/11/13 18:00 | Concord University Mountain Lions v Unc Pembroke Braves | L | 28-25 |
| NCAAF | 2021/11/06 16:00 | Unc Pembroke Braves v Notre Dame Falcons | L | 7-45 |
| NCAAF | 2021/10/30 16:00 | West Liberty v Unc Pembroke Braves | W | 17-27 |
| NCAAF | 2021/10/23 18:00 | Unc Pembroke Braves v University of Charleston Golden Eagles | W | 21-14 |
| NCAAF | 2021/10/16 22:00 | West Virginia State Yellow Jackets v Unc Pembroke Braves | W | 13-14 |
| NCAAF | 2021/10/09 16:00 | Unc Pembroke Braves v Wheeling | W | 34-28 |
| NCAAF | 2021/10/02 17:00 | Frostburg State v Unc Pembroke Braves | L | 51-21 |
| NCAAF | 2021/09/25 17:00 | Unc Pembroke Braves v Fairmont State | L | 27-30 |