Stadium: Saints Field Round: 1
| NCAAF | 2021/11/06 18:00 | St Scholastica Saints v Macalester Scots | L | 14-28 |
| NCAAF | 2021/10/30 18:00 | St Johns Johnnies v St Scholastica Saints | L | 81-0 |
| NCAAF | 2021/10/23 18:00 | St Olaf Oles v St Scholastica Saints | L | 41-14 |
| NCAAF | 2021/10/16 18:30 | St Scholastica Saints v Carleton Knights | L | 14-30 |
| NCAAF | 2021/10/09 18:00 | St Scholastica Saints v Gustavus Adolphus Gusties | L | 7-72 |
| NCAAF | 2021/10/02 18:00 | Hamline Pipers v St Scholastica Saints | L | 34-18 |
| NCAAF | 2021/09/25 18:00 | St Scholastica Saints v Augsburg Auggies | L | 14-54 |
| NCAAF | 2019/11/16 18:00 | St Scholastica Saints v Macmurray Highlanders | L | 20-35 |
| NCAAF | 2021/11/27 18:00 | St Johns Johnnies v Linfield Wildcats | L | 28-31 |
| NCAAF | 2021/11/20 18:00 | St Johns Johnnies v Lake Forest Foresters | W | 41-14 |
| NCAAF | 2021/11/06 18:00 | Carleton Knights v St Johns Johnnies | W | 10-38 |
| NCAAF | 2021/10/30 18:00 | St Johns Johnnies v St Scholastica Saints | W | 81-0 |
| NCAAF | 2021/10/23 18:00 | Gustavus Adolphus Gusties v St Johns Johnnies | W | 7-37 |
| NCAAF | 2021/10/16 18:00 | St Johns Johnnies v St Olaf Oles | W | 56-0 |
| NCAAF | 2021/10/09 18:00 | St Johns Johnnies v Augsburg Auggies | W | 50-0 |
| NCAAF | 2021/10/02 18:00 | Concordia-Moorhead Cobbers v St Johns Johnnies | W | 0-49 |